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A type of localized scleroderma characterized by a long strip of indurated skin, which is typically found unilaterally on an arm or leg, and sometimes on the forehead or trunk. This disorder often affects the tissues beneath the skin, causing damage to bones, muscle or other organs. It can limit movement, alter growth, and disfigure the affected area.
Biomarker and diagnostic research for linear scleroderma has been reported in the published literature.
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
60 publications have been identified in PubMed for linear scleroderma. Research spans Case Report / Case Series (53%), Review / Meta-Analysis (12%), and Gene Therapy / Novel Therapeutics (10%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 32 | 53% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 7:07 AM UTC
Genetic and Rare Diseases Info Center
Research summaries |
7 |
12% |
New treatment approaches | 6 | 10% |
Disease patterns and progression | 5 | 8% |
Testing and diagnosis research | 4 | 7% |
Laboratory research | 3 | 5% |
Other research | 2 | 3% |
Clinical study results | 1 | 2% |
Zheng R (2026). [PMID: 41593653](https://pubmed.ncbi.nlm.nih.gov/41593653/). *Pediatric rheumatology online journal*. [Case Report / Case Series]
Tesauro P (2026). [PMID: 40420729](https://pubmed.ncbi.nlm.nih.gov/40420729/). *Dermatology reports*. [Case Report / Case Series]
Chang X (2026). [PMID: 41737215](https://pubmed.ncbi.nlm.nih.gov/41737215/). *Frontiers in immunology*. [Epidemiology / Natural History]
Han GM (2026). [PMID: 40971809](https://pubmed.ncbi.nlm.nih.gov/40971809/). *Rheumatology (Oxford, England)*. [Basic Science / Preclinical]
Tzourmpaki NG (2026). [PMID: 41289972](https://pubmed.ncbi.nlm.nih.gov/41289972/). *Annales de dermatologie et de venereologie*. [Case Report / Case Series]
Zavala Gottau P (2026). [PMID: 41577439](https://pubmed.ncbi.nlm.nih.gov/41577439/). *Practical neurology*. [Case Report / Case Series]
Ai X (2026). [PMID: 41773608](https://pubmed.ncbi.nlm.nih.gov/41773608/). *The Journal of dermatological treatment*. [Case Report / Case Series]
Mosleh R (2026). [PMID: 41847274](https://pubmed.ncbi.nlm.nih.gov/41847274/). *Neuro-ophthalmology (Aeolus Press)*. [Case Report / Case Series]
Kilic Konte E (2026). [PMID: 42044443](https://pubmed.ncbi.nlm.nih.gov/42044443/). *Turk Arch Pediatr*. [Epidemiology / Natural History]
Jensen C (2026). [PMID: 42005244](https://pubmed.ncbi.nlm.nih.gov/42005244/). *Cureus*. [Case Report / Case Series]
AI-curated news mentioning linear scleroderma
Updated Jul 20, 2026
A literature review highlights the rare occurrence of orbital involvement in linear scleroderma, presenting an unusual case that adds to the understanding of this condition. This study may inform future research and clinical approaches to managing linear scleroderma.