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localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms

MONDO:0019584

Overview

Localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms is a form of atypical lichen myxedematosus, characterized by the appearance of several 2-4 mm erythematous waxy papules confined to a few sites that may be associated with either an immunoglobulin A (IgA) nephropathy in patients with acral persistent papular mucinosis; discrete papular lichen myxedematosus; a scleromyxedema-like involvement, with dysphagia, hoarseness, pulmonary involvement, and carpal tunnel syndrome; myositis without skin sclerosis; or paraproteinemia.

Diagnosis

Biomarker and diagnostic research for localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms.

203 publications have been identified in PubMed for localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms. Kisho has analyzed 103 by research type. Research spans Review / Meta-Analysis (46%), Epidemiology / Natural History (17%), and Case Report / Case Series (16%).

Research Type	Count	% of Total
Research summaries	47

Data assembled from 3 of 12 sources · Last updated Sep 21, 2026, 4:53 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:90399

GARD

Genetic and Rare Diseases Info Center

GARD:19143

Questions for Your Care Team

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localized lichen myxedematosus with monoclonal gammopathy or systemic symptoms

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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