Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Logopenic progressive aphasia (lv-PPA) is a form of primary progressive aphasia (PPA), characterized by impaired single-word retrieval and naming and impaired repetition with spared single-word comprehension and object knowledge.
Biomarker and diagnostic research for logopenic progressive aphasia has been reported in the published literature.
9 clinical trials registered, 6 recruiting. Interventions under study include other interventions, medical devices, and drug therapy. Pipeline includes 1 PHASE2, 1 EARLY_PHASE1, 7 NA. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT03887481](https://clinicaltrials.gov/study/NCT03887481) |
Data assembled from 4 of 12 sources · Last updated Sep 17, 2026, 11:49 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Targeting Language-specific and Executive-control Networks With Transcranial Direct Current Stimulation in Logopenic Variant PPA |
NA |
Johns Hopkins University |
RECRUITING |
[NCT05386394](https://clinicaltrials.gov/study/NCT05386394) | Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia | PHASE2 | Johns Hopkins University | RECRUITING |
[NCT06538311](https://clinicaltrials.gov/study/NCT06538311) | Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease | EARLY_PHASE1 | Massachusetts General Hospital | RECRUITING |
[NCT04881617](https://clinicaltrials.gov/study/NCT04881617) | Treatment for Speech and Language in Primary Progressive Aphasia | NA | University of Texas at Austin | ACTIVE_NOT_RECRUITING |
[NCT04122001](https://clinicaltrials.gov/study/NCT04122001) | Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease | NA | Johns Hopkins University | UNKNOWN |
51 publications have been identified in PubMed for logopenic progressive aphasia. Research spans Basic Science / Preclinical (24%), Diagnostic / Biomarker (18%), and Case Report / Case Series (18%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 12 | 24% |
Testing and diagnosis research | 9 | 18% |
Patient case studies | 9 | 18% |
Disease patterns and progression | 8 | 16% |
Research summaries | 7 | 14% |
Clinical study results | 4 | 8% |
Other research | 2 | 4% |
Koenig KA (2026). [PMID: 41247916](https://pubmed.ncbi.nlm.nih.gov/41247916/). *J Alzheimers Dis*. [Basic Science / Preclinical]
Akaike S (2026). [PMID: 42143996](https://pubmed.ncbi.nlm.nih.gov/42143996/). *J Neurol Sci*. [Case Report / Case Series]
Okoye O (2026). [PMID: 41709596](https://pubmed.ncbi.nlm.nih.gov/41709596/). *Neurocase*. [Case Report / Case Series]
Tomasoni R (2026). [PMID: 41948541](https://pubmed.ncbi.nlm.nih.gov/41948541/). *Alzheimers Dement (Amst)*. [Case Report / Case Series]
Macoir J (2026). [PMID: 42022240](https://pubmed.ncbi.nlm.nih.gov/42022240/). *Front Hum Neurosci*. [Basic Science / Preclinical]
Pereira FL (2026). [PMID: 41959086](https://pubmed.ncbi.nlm.nih.gov/41959086/). *bioRxiv*. [Epidemiology / Natural History]
Cordonier N (2026). [PMID: 42186116](https://pubmed.ncbi.nlm.nih.gov/42186116/). *Alzheimers Dement*. [Epidemiology / Natural History]
Vonk JMJ (2026). [PMID: 41554669](https://pubmed.ncbi.nlm.nih.gov/41554669/). *Alzheimers Dement*. [Basic Science / Preclinical]
Macoir J (2026). [PMID: 42179085](https://pubmed.ncbi.nlm.nih.gov/42179085/). *J Alzheimers Dis*. [Basic Science / Preclinical]
Strobel J (2026). [PMID: 41723928](https://pubmed.ncbi.nlm.nih.gov/41723928/). *Neuroimage Clin*. [Diagnostic / Biomarker]
AI-curated news mentioning logopenic progressive aphasia
Updated Aug 6, 2026
A recent survey study highlights the current state of speech and language therapy for individuals with primary progressive aphasia (PPA) in Germany. The findings aim to improve care strategies and inform future research in this area.