Lyme disease (named after the towns in the USA where the disease was first identified) is a bacterial infection caused by Borrelia burgdorferi.
Comprehensive, easy-to-understand information about this condition
How we create this content →The documentation surrounding Lyme disease is limited due to its complex nature and the variability in symptoms among affected individuals. Additionally, Lyme disease affects fewer than 300,000 people annually in the U.S., which can hinder extensive clinical studies. The overlap of symptoms with other conditions further complicates accurate characterization and understanding of the disease.
To navigate Lyme disease effectively, consider consulting an infectious disease specialist with experience in tick-borne illnesses. Engaging with patient organizations like LymeDisease.org can provide valuable resources and community support. Additionally, participating in clinical trials may offer access to cutting-edge treatments and contribute to ongoing research efforts. For genetic counseling resources, the National Society of Genetic Counselors maintains a directory at findageneticcounselor.com.
Currently, there are 38 active clinical trials investigating various aspects of Lyme disease, including treatment options and disease management strategies. These trials are crucial for advancing our understanding and developing effective therapies. For more information on specific trials, you can visit the ClinicalTrials.gov search page: https://clinicaltrials.gov/search?cond=Lyme%20disease.
Actionable guidance for navigating care for Lyme disease
To navigate Lyme disease effectively, consider consulting an infectious disease specialist with experience in tick-borne illnesses. Engaging with patient organizations like LymeDisease.org can provide valuable resources and community support. Additionally, participating in clinical trials may offer access to cutting-edge treatments and contribute to ongoing research efforts. For genetic counseling resources, the National Society of Genetic Counselors maintains a directory at findageneticcounselor.com.
Consider asking your healthcare providers these condition-specific questions
Connect with organizations supporting the Lyme disease community
Helpful links for rare disease information and support
The documentation surrounding Lyme disease is limited due to its complex nature and the variability in symptoms among affected individuals. Additionally, Lyme disease affects fewer than 300,000 people annually in the U.S., which can hinder extensive clinical studies. The overlap of symptoms with other conditions further complicates accurate characterization and understanding of the disease.
To navigate Lyme disease effectively, consider consulting an infectious disease specialist with experience in tick-borne illnesses. Engaging with patient organizations like LymeDisease.org can provide valuable resources and community support. Additionally, participating in clinical trials may offer access to cutting-edge treatments and contribute to ongoing research efforts. For genetic counseling resources, the National Society of Genetic Counselors maintains a directory at findageneticcounselor.com.
Currently, there are 38 active clinical trials investigating various aspects of Lyme disease, including treatment options and disease management strategies. These trials are crucial for advancing our understanding and developing effective therapies. For more information on specific trials, you can visit the ClinicalTrials.gov search page: https://clinicaltrials.gov/search?cond=Lyme%20disease.
Actionable guidance for navigating care for Lyme disease
To navigate Lyme disease effectively, consider consulting an infectious disease specialist with experience in tick-borne illnesses. Engaging with patient organizations like LymeDisease.org can provide valuable resources and community support. Additionally, participating in clinical trials may offer access to cutting-edge treatments and contribute to ongoing research efforts. For genetic counseling resources, the National Society of Genetic Counselors maintains a directory at findageneticcounselor.com.
Consider asking your healthcare providers these condition-specific questions
Connect with organizations supporting the Lyme disease community
Helpful links for rare disease information and support
The documentation surrounding Lyme disease is limited due to its complex nature and the variability in symptoms among affected individuals. Additionally, Lyme disease affects fewer than 300,000 people annually in the U.S., which can hinder extensive clinical studies. The overlap of symptoms with other conditions further complicates accurate characterization and understanding of the disease.
To navigate Lyme disease effectively, consider consulting an infectious disease specialist with experience in tick-borne illnesses. Engaging with patient organizations like LymeDisease.org can provide valuable resources and community support. Additionally, participating in clinical trials may offer access to cutting-edge treatments and contribute to ongoing research efforts. For genetic counseling resources, the National Society of Genetic Counselors maintains a directory at findageneticcounselor.com.
Currently, there are 38 active clinical trials investigating various aspects of Lyme disease, including treatment options and disease management strategies. These trials are crucial for advancing our understanding and developing effective therapies. For more information on specific trials, you can visit the ClinicalTrials.gov search page: https://clinicaltrials.gov/search?cond=Lyme%20disease.
Actionable guidance for navigating care for Lyme disease
To navigate Lyme disease effectively, consider consulting an infectious disease specialist with experience in tick-borne illnesses. Engaging with patient organizations like LymeDisease.org can provide valuable resources and community support. Additionally, participating in clinical trials may offer access to cutting-edge treatments and contribute to ongoing research efforts. For genetic counseling resources, the National Society of Genetic Counselors maintains a directory at findageneticcounselor.com.
Consider asking your healthcare providers these condition-specific questions
Connect with organizations supporting the Lyme disease community
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Feb 8, 2026
Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.
Consider asking your healthcare providers these condition-specific questions
European rare disease database
2 peer-reviewed sources from PubMed
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.
AI-curated news mentioning Lyme disease
Updated Feb 2, 2026
En Carta Diagnostics' EC Pocket Lyme test has received FDA Breakthrough Device Designation, aiming to improve diagnosis for the approximately 476,000 new Lyme disease cases reported annually in the US. This designation may expedite the test's development and review process.
Clinical trials for new Lyme disease vaccines are currently underway, but no vaccine is available yet. This highlights ongoing efforts to address Lyme disease prevention amid rising cases.
The CDC estimates that approximately 300,000 Americans are diagnosed with Lyme disease annually. This data was shared at the 2013 International Conference on Lyme Borreliosis and Other Tick-Borne Diseases in Boston.
The CDC highlights Lyme Disease Awareness Month, urging Americans to educate themselves about this tickborne disease. The campaign aims to promote protective measures for those in areas with Lyme disease activity.
The CDC reports that Lyme disease cases have more than doubled since 1991, highlighting a significant public health concern. Notably, 93% of these cases are concentrated in just 10 states, emphasizing the need for targeted awareness and prevention efforts.