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An antiquated term that refers to a non-Hodgkin lymphoma composed of small and medium sized lymphocytes.
Biomarker and diagnostic research for lymphosarcoma has been reported in the published literature.
1 FDA-approved treatment is available for lymphosarcoma, including CHLORAMBUCIL (LEUKERAN, approved 1957).
Brand Name | Generic Name | Mechanism | Approved | Market Status |
|---|---|---|---|---|
223 clinical trials registered, 64 recruiting. Interventions under study include drug therapy, other interventions, biologic therapy, and medical devices. Pipeline includes 2 PHASE4, 11 PHASE3, 44 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05929612](https://clinicaltrials.gov/study/NCT05929612) |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 12:47 AM UTC
Genetic and Rare Diseases Info Center
CHLORAMBUCIL |
— |
1957 |
Available |
Gene therapy approaches for lymphosarcoma have been reported in the published literature.
223 trials found
A Study of Response Adapted Ultra Low Dose 4 Gy Radiation for Definitive Therapy of Marginal Zone Lymphoma |
PHASE2 |
M.D. Anderson Cancer Center |
RECRUITING |
[NCT06563596](https://clinicaltrials.gov/study/NCT06563596) | Epco, Zanu, Ritux for R/R FL or MZL | PHASE2 | Reid Merryman, MD | RECRUITING |
[NCT06826118](https://clinicaltrials.gov/study/NCT06826118) | Axicabtagene Ciloleucel Injection in Patients With Relapsed/Refractory Follicular Lymphoma | PHASE2 | The First Affiliated Hospital of Xiamen University | RECRUITING |
[NCT06941194](https://clinicaltrials.gov/study/NCT06941194) | Preventive Application of Single-use Negative Pressure Wound Therapy (sNPWT) in the Postoperative Course of Radiotreatated Limb Sarcoma Surgery | NA | Istituto Oncologico Veneto IRCCS | RECRUITING |
[NCT05334069](https://clinicaltrials.gov/study/NCT05334069) | Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection | — | Alliance for Clinical Trials in Oncology | RECRUITING |
24 publications have been identified in PubMed for lymphosarcoma. Research spans Basic Science / Preclinical (29%), Epidemiology / Natural History (29%), and Case Report / Case Series (17%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 7 | 29% |
Disease patterns and progression | 7 | 29% |
Patient case studies | 4 | 17% |
Research summaries | 3 | 13% |
Testing and diagnosis research | 2 | 8% |
New treatment approaches | 1 | 4% |
Ji S (2026). [PMID: 41689038](https://pubmed.ncbi.nlm.nih.gov/41689038/). *BMC Vet Res*. [Case Report / Case Series]
Ramos DD (2026). [PMID: 41769524](https://pubmed.ncbi.nlm.nih.gov/41769524/). *Cureus*. [Case Report / Case Series]
Awad MS (2026). [PMID: 41596216](https://pubmed.ncbi.nlm.nih.gov/41596216/). *Int J Mol Sci*. [Basic Science / Preclinical]
Yu R (2026). [PMID: 41971019](https://pubmed.ncbi.nlm.nih.gov/41971019/). *Transbound Emerg Dis*. [Review / Meta-Analysis]
Moralev AD (2025). [PMID: 41465338](https://pubmed.ncbi.nlm.nih.gov/41465338/). *Int J Mol Sci*. [Basic Science / Preclinical]
Moran PE (2025). [PMID: 40261441](https://pubmed.ncbi.nlm.nih.gov/40261441/). *Vet Res Commun*. [Epidemiology / Natural History]
Cordella A (2025). [PMID: 41133985](https://pubmed.ncbi.nlm.nih.gov/41133985/). *J Feline Med Surg*. [Diagnostic / Biomarker]
Huang D (2025). [PMID: 40230427](https://pubmed.ncbi.nlm.nih.gov/40230427/). *Oncol Lett*. [Case Report / Case Series]
Petersen MI (2025). [PMID: 40932257](https://pubmed.ncbi.nlm.nih.gov/40932257/). *Microbiol Spectr*. [Basic Science / Preclinical]
Fonteque GV (2025). [PMID: 40008759](https://pubmed.ncbi.nlm.nih.gov/40008759/). *Braz J Biol*. [Epidemiology / Natural History]