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mediastinal gray zone lymphoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

mediastinal gray zone lymphoma

MONDO:0004020

Also known as:mediastinal B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and Classic Hodgkin lymphomamediastinal B-cell lymphoma, unclassifiable, with features Intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphomamediastinal Grey zone lymphoma

Overview

A mediastinal lymphoma with molecular, morphologic, immunophenotypic, and clinical features of both mediastinal (thymic) large B-cell lymphoma and classical Hodgkin lymphoma. The identification of this group of lymphomas, along with recent gene expression profiling results (PDL2 gene expression in both mediastinal (thymic) large B-cell lymphoma tissues and Hodgkin lymphoma cell lines), further supports the hypothesis that mediastinal (thymic) large B-cell lymphomas and classical Hodgkin lymphomas are related entities.

Diagnosis

Biomarker and diagnostic research for mediastinal gray zone lymphoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for mediastinal gray zone lymphoma.

10 publications have been identified in PubMed for mediastinal gray zone lymphoma. Research spans Review / Meta-Analysis (50%), Case Report / Case Series (30%), and Diagnostic / Biomarker (10%).

Research Type	Count	% of Total
Research summaries	5	50%

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 3:57 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

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mediastinal gray zone lymphoma

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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