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Meesmann corneal dystrophy (MECD) is a rare form of superficial corneal dystrophy characterized by distinct tiny bubble-like, round-to-oval punctate bilateral opacities in the central corneal epithelium, and to a lesser extent in the peripheral cornea, with little impact on vision.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for Meesmann corneal dystrophy.
8 publications have been identified in PubMed for Meesmann corneal dystrophy. Research spans Case Report / Case Series (50%), Review / Meta-Analysis (38%), and Gene Therapy / Novel Therapeutics (13%).
Charoenrook V (2026). [PMID: 41683752](https://pubmed.ncbi.nlm.nih.gov/41683752/). *International journal of molecular sciences*. [Case Report / Case Series]
Sneyers A (2026). [PMID: 40974359](https://pubmed.ncbi.nlm.nih.gov/40974359/). *Ophthalmology*. [Case Report / Case Series]
Moshirfar M (2026). [PMID: 32491788](https://pubmed.ncbi.nlm.nih.gov/32491788/). *Unknown Journal*. [Review / Meta-Analysis]
Qiu J (2026). [PMID: 42053878](https://pubmed.ncbi.nlm.nih.gov/42053878/). *Jpn J Ophthalmol*. [Case Report / Case Series]
Liskova P (2025). [PMID: 40079222](https://pubmed.ncbi.nlm.nih.gov/40079222/). *Clinical & experimental ophthalmology*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Oct 4, 2026, 3:01 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Meesmann corneal dystrophy
Huang X (2025). [PMID: 40911248](https://pubmed.ncbi.nlm.nih.gov/40911248/). *International ophthalmology*. [Review / Meta-Analysis]
McLain A (2025). [PMID: 41110473](https://pubmed.ncbi.nlm.nih.gov/41110473/). *Journal of controlled release : official journal of the Controlled Release Society*. [Gene Therapy / Novel Therapeutics]
De Faria A (2025). [PMID: 39941522](https://pubmed.ncbi.nlm.nih.gov/39941522/). *Journal of clinical medicine*. [Case Report / Case Series]
AI-curated news mentioning Meesmann corneal dystrophy
Updated Apr 29, 2026
A case study highlights secondary corneal amyloidosis in a patient with Meesmann corneal dystrophy, providing insights into the relationship between these two conditions. This research contributes to the understanding of corneal dystrophies and their complications.