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A disease of the inner ear (labyrinth) that is characterized by fluctuating sensorineural hearing loss; tinnitus; episodic vertigo; and aural fullness. It is the most common form of endolymphatic hydrops.
Features include: Hearing loss (hearing impairment), Vertigo, and Tinnitus.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Ears | 3 | Hearing loss (hearing impairment), Vertigo, Tinnitus |
Biomarker and diagnostic research for Meniere disease has been reported in the published literature.
13 clinical trials registered, 6 recruiting. Interventions under study include drug therapy, other interventions, medical devices, and gene therapy. Pipeline includes 1 PHASE4, 2 PHASE3, 2 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05851508](https://clinicaltrials.gov/study/NCT05851508) |
Data assembled from 6 of 12 sources · Last updated Sep 20, 2026, 11:14 AM UTC
Online Mendelian Inheritance in Man
European rare disease database
Common questions about Meniere disease
The Effecttiveness of Intratympanic Methylprednisolon Injections Compared to Placebo in the Treatment of Vertigo Attacks in Meniere's Disease |
PHASE3 |
Leiden University Medical Center |
RECRUITING |
[NCT07518069](https://clinicaltrials.gov/study/NCT07518069) | Genetic and Biohumoral Factors Involved in Menière's Disease and Their Correlation With Phenotypes | — | IRCCS San Raffaele | RECRUITING |
[NCT05424302](https://clinicaltrials.gov/study/NCT05424302) | Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy | NA | University of British Columbia | RECRUITING |
[NCT07272473](https://clinicaltrials.gov/study/NCT07272473) | Effects of Cervical Mobilization on Dizziness, Balance, and Joint Position Sense in Patients With Meniere's Disease | NA | Abant Izzet Baysal University | RECRUITING |
[NCT03587701](https://clinicaltrials.gov/study/NCT03587701) | Effects of Anakinra in Subjects With Corticosteroid-resistant/Intolerant Meniere's Disease and Autoimmune Inner Ear Disease | PHASE2 | Northwell Health | RECRUITING |
351 publications have been identified in PubMed for Meniere disease. Kisho has analyzed 157 by research type. Research spans Review / Meta-Analysis (27%), Basic Science / Preclinical (23%), and Epidemiology / Natural History (23%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 42 | 27% |
Laboratory research | 36 | 23% |
Disease patterns and progression | 36 | 23% |
Testing and diagnosis research | 19 | 12% |
Clinical study results | 19 | 12% |
Other research | 2 | 1% |
New treatment approaches | 2 | 1% |
Patient case studies | 1 | 1% |
Wang J (2026). [PMID: 41636232](https://pubmed.ncbi.nlm.nih.gov/41636232/). *Acta Otolaryngol*. [Diagnostic / Biomarker]
Parihar S (2026). [PMID: 40525902](https://pubmed.ncbi.nlm.nih.gov/40525902/). *Ann R Coll Surg Engl*. [Basic Science / Preclinical]
Chen JY (2026). [PMID: 41644458](https://pubmed.ncbi.nlm.nih.gov/41644458/). *Zhonghua Yi Xue Za Zhi*. [Clinical Trial Publication]
Sasano Y (2026). [PMID: 41562919](https://pubmed.ncbi.nlm.nih.gov/41562919/). *Med Sci (Basel)*. [Epidemiology / Natural History]
Tan W (2026). [PMID: 41124383](https://pubmed.ncbi.nlm.nih.gov/41124383/). *J Vestib Res*. [Epidemiology / Natural History]
Martínez HG (2026). [PMID: 41241712](https://pubmed.ncbi.nlm.nih.gov/41241712/). *Eur Arch Otorhinolaryngol*. [Review / Meta-Analysis]
Sekulic M (2026). [PMID: 41752086](https://pubmed.ncbi.nlm.nih.gov/41752086/). *Int J Mol Sci*. [Diagnostic / Biomarker]
Si N (2026). [PMID: 42216666](https://pubmed.ncbi.nlm.nih.gov/42216666/). *J Vestib Res*. [Review / Meta-Analysis]
Takemiya Y (2026). [PMID: 41771047](https://pubmed.ncbi.nlm.nih.gov/41771047/). *Acta Otolaryngol*. [Epidemiology / Natural History]
Vanneste S (2026). [PMID: 42168216](https://pubmed.ncbi.nlm.nih.gov/42168216/). *Nat Rev Dis Primers*. [Review / Meta-Analysis]
AI-curated news mentioning Meniere disease
Updated Dec 19, 2025
A study identifies a rare variant in the TRIOBP gene associated with occupational noise exposure in Meniere disease. This discovery could enhance understanding of genetic factors influencing the disease.