Meningeal Tuberculosis — Clinical Trials

MONDO:00060426 active·3 recruitingLast updated: Mar 16, 2026, 4:03 AM

Trial Landscape

Meningeal Tuberculosis has a growing clinical research program, driven by drug treatment.

Recruiting

Active Trials

By Approach

Drug Treatment6

By Phase

Phase 1

Phase 2

Phase 3

Sponsor Types

Academic/Other5NIH1

Trial Locations

India2 trials

Uganda2 trials

Brazil2 trials

South Africa2 trials

China1 trial

United States1 trial

Kenya1 trial

Malawi1 trial

Mexico1 trial

Peru1 trial

Trials often recruit across multiple countries, so totals exceed the trial count.

6 Trials

Phase 3Recruiting

NCT04145258

Intensified Tuberculosis Treatment to Reduce the Mortality of Patients With Tuberculous Meningitis

Sponsor:ANRS, Emerging Infectious Diseases

Côte d’IvoireStarted: Feb 2021Est. completion: Apr 2026Updated: Jan 2024

Last updated over 18 months ago

Phase 2Recruiting

NCT05590455

Tnf Inhibitors to Reduce Mortality in HIV-1 Infected PAtients With Tuberculosis meNIngitis

Sponsor:ANRS, Emerging Infectious Diseases

BrazilStarted: Apr 2023Est. completion: Dec 2027Updated: Dec 2025

Phase 2Recruiting

NCT05383742

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Sponsor:National Institute of Allergy and Infectious Diseases (NIAID)

BrazilStarted: Dec 2023Est. completion: Sep 2029Updated: Dec 2025

Phase 1Enrolling by Invitation

NCT06811025

Phase II Clinical Study of Contezolid for the Treatment of Tuberculous Meningitis

Sponsor:Beijing Chest Hospital

ChinaStarted: Feb 2024Est. completion: Dec 2025Updated: Feb 2025

Phase 3Not Yet Recruiting

NCT05917340

Intensified Short Course Regimen for TBM in Adults

Sponsor:Indian Council of Medical Research

IndiaStarted: Mar 2024Est. completion: Sep 2027Updated: Dec 2023

Last updated over 18 months ago

Phase 2Not Yet Recruiting

NCT07227779

B-PaLMZ for TB Meningitis

Sponsor:University of Minnesota

United StatesStarted: Feb 2026Est. completion: Aug 2030Updated: Nov 2025

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Data sourced from ClinicalTrials.gov via Kisho's automated pipeline. Trials refreshed every 4 hours for monitored diseases.

Last sync: March 16, 2026 at 4:03 AM