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Estimated prevalence: 1-9 in 100,000 (Uncommon).
No clinical trials have been registered for methotrexate toxicity.
143 publications have been identified in PubMed for methotrexate toxicity. Research spans Basic Science / Preclinical (57%), Case Report / Case Series (22%), and Epidemiology / Natural History (9%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 81 | 57% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 12:58 PM UTC
European rare disease database
32 |
22% |
Disease patterns and progression | 13 | 9% |
Research summaries | 10 | 7% |
Other research | 4 | 3% |
Clinical study results | 3 | 2% |
Sarman E (2026). [PMID: 41828341](https://pubmed.ncbi.nlm.nih.gov/41828341/). *Int J Mol Sci*. [Basic Science / Preclinical]
Kabartan E (2026). [PMID: 40632157](https://pubmed.ncbi.nlm.nih.gov/40632157/). *Naunyn Schmiedebergs Arch Pharmacol*. [Epidemiology / Natural History]
Grofvert J (2026). [PMID: 41792836](https://pubmed.ncbi.nlm.nih.gov/41792836/). *J Med Case Rep*. [Review / Meta-Analysis]
Mohamed AA (2026). [PMID: 41980395](https://pubmed.ncbi.nlm.nih.gov/41980395/). *Int Immunopharmacol*. [Basic Science / Preclinical]
Mohyeldin RH (2026). [PMID: 41396268](https://pubmed.ncbi.nlm.nih.gov/41396268/). *Naunyn Schmiedebergs Arch Pharmacol*. [Basic Science / Preclinical]
Clark KA (2026). [PMID: 41658808](https://pubmed.ncbi.nlm.nih.gov/41658808/). *Cureus*. [Case Report / Case Series]
Dugad A (2026). [PMID: 41587872](https://pubmed.ncbi.nlm.nih.gov/41587872/). *Ann Afr Med*. [Case Report / Case Series]
Moss M (2026). [PMID: 42007941](https://pubmed.ncbi.nlm.nih.gov/42007941/). *Clin Toxicol (Phila)*. [Epidemiology / Natural History]
García-Guzmán AD (2026). [PMID: 41074647](https://pubmed.ncbi.nlm.nih.gov/41074647/). *Pediatr Blood Cancer*. [Basic Science / Preclinical]
Genc A (2026). [PMID: 41942837](https://pubmed.ncbi.nlm.nih.gov/41942837/). *J Biochem Mol Toxicol*. [Basic Science / Preclinical]