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Features include: Mitral regurgitation and Mitral valve prolapse.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 2 | Mitral regurgitation, Mitral valve prolapse |
DCHS1 encodes dachsous cadherin-related 1 (3,298 aa). Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. Highest expression in Uterus (67.0 TPM) and Cervix Endocervix (40.8 TPM).
Mitral valve prolapse, myxomatous 2 is associated with mutations in the DCHS1 gene on chromosome 11.
DCHS1 is classified as a druggable target with score 0.0.
Genetic testing for DCHS1 is available. Testing is considered confirmatory for diagnosis.
No clinical trials have been registered for mitral valve prolapse, myxomatous 2.
1 publication has been identified in PubMed for mitral valve prolapse, myxomatous 2. Research spans Review / Meta-Analysis (100%).
Wang E (2026). [PMID: 41717582](https://pubmed.ncbi.nlm.nih.gov/41717582/). *Frontiers in cardiovascular medicine*. [Review / Meta-Analysis]
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 9:22 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
AI-curated news mentioning mitral valve prolapse, myxomatous 2
Updated Jul 22, 2026
The MITPROL AR-PL Registry reveals critical insights into the prevalence and clinical significance of arrhythmic mitral valve prolapse. This study identifies key risk factors associated with the condition, enhancing understanding for future research and treatment strategies.