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Features include: Disproportionate tall stature, Striae distensae, Reversed usual vertebral column curves, and Pectus excavatum and 4 more.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Head and neck | 2 | High, narrow palate, High palate |
Heart and blood vessels |
13 clinical trials registered, 7 recruiting. Interventions under study include other interventions, procedural interventions, medical devices, and drug therapy. Pipeline includes 1 PHASE3, 4 NA. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT04190602](https://clinicaltrials.gov/study/NCT04190602) |
Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 6:45 AM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
Common questions about MVP1
2 |
Mitral regurgitation, Mitral valve prolapse |
Growth and development | 1 | Disproportionate tall stature |
Bones and joints | 1 | Reversed usual vertebral column curves |
Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System |
— |
NeoChord |
RECRUITING |
[NCT06341166](https://clinicaltrials.gov/study/NCT06341166) | Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse | — | Centro Cardiologico Monzino | RECRUITING |
[NCT06255457](https://clinicaltrials.gov/study/NCT06255457) | Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery | — | Karolinska Institutet | RECRUITING |
[NCT07384871](https://clinicaltrials.gov/study/NCT07384871) | AI-Based Shape and Function Analysis of Mitral Valve Prolapse Using 3D Ultrasound | — | IRCCS Policlinico S. Donato | RECRUITING |
[NCT03113552](https://clinicaltrials.gov/study/NCT03113552) | Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty | — | Centre Hospitalier Universitaire, Amiens | RECRUITING |
21 publications have been identified in PubMed for MVP1. Research spans Clinical Trial Publication (45%), Basic Science / Preclinical (25%), and Review / Meta-Analysis (15%).
Research Type | Count | % of Total |
|---|---|---|
Clinical study results | 9 | 45% |
Laboratory research | 5 | 25% |
Research summaries | 3 | 15% |
Patient case studies | 3 | 15% |
Kölling R (2026). [PMID: 41883240](https://pubmed.ncbi.nlm.nih.gov/41883240/). *Biol Open*. [Basic Science / Preclinical]
Bichler M (2026). [PMID: 41967854](https://pubmed.ncbi.nlm.nih.gov/41967854/). *Interdiscip Cardiovasc Thorac Surg*. [Clinical Trial Publication]
Torii Y (2025). [PMID: 40875281](https://pubmed.ncbi.nlm.nih.gov/40875281/). *Echocardiography (Mount Kisco, N.Y.)*. [Clinical Trial Publication]
Boudoulas KD (2025). [PMID: 39226885](https://pubmed.ncbi.nlm.nih.gov/39226885/). *Cardiology*. [Review / Meta-Analysis]
Rodrigues E (2025). [PMID: 40300595](https://pubmed.ncbi.nlm.nih.gov/40300595/). *Cell host & microbe*. [Basic Science / Preclinical]
Covantsev S (2025). [PMID: 41089768](https://pubmed.ncbi.nlm.nih.gov/41089768/). *Reviews in cardiovascular medicine*. [Review / Meta-Analysis]
Takahashi K (2025). [PMID: 41448542](https://pubmed.ncbi.nlm.nih.gov/41448542/). *Journal of thrombosis and haemostasis : JTH*. [Basic Science / Preclinical]
Ward HD (2025). [PMID: 40527704](https://pubmed.ncbi.nlm.nih.gov/40527704/). *Trends in parasitology*. [Basic Science / Preclinical]
Aquilina J (2025). [PMID: 39404042](https://pubmed.ncbi.nlm.nih.gov/39404042/). *Perfusion*. [Case Report / Case Series]
Luo F (2025). [PMID: 40104901](https://pubmed.ncbi.nlm.nih.gov/40104901/). *Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences*. [Review / Meta-Analysis]