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Features include: Mitral regurgitation and Mitral valve prolapse.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 2 | Mitral regurgitation, Mitral valve prolapse |
DZIP1 encodes DAZ interacting zinc finger protein 1 (867 aa). Molecular adapter that recruits protein complexes required for cilium assembly and function to the cilium basal body. Highest expression in Testis (43.6 TPM) and Brain Cerebellar Hemisphere (34.3 TPM).
Mitral valve prolapse, myxomatous 3 is associated with mutations in the DZIP1 gene on chromosome 13.
DZIP1 is classified as a druggable target with score 0.0.
Genetic testing for DZIP1 is available. Testing is considered confirmatory for diagnosis.
No clinical trials have been registered for mitral valve prolapse, myxomatous 3.
1 publication has been identified in PubMed for mitral valve prolapse, myxomatous 3. Research spans Review / Meta-Analysis (100%).
Wang E (2026). [PMID: 41717582](https://pubmed.ncbi.nlm.nih.gov/41717582/). *Frontiers in cardiovascular medicine*. [Review / Meta-Analysis]
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 2:59 PM UTC
Online Mendelian Inheritance in Man
Genetic and Rare Diseases Info Center
AI-curated news mentioning mitral valve prolapse, myxomatous 3
Updated Jul 22, 2026
The MITPROL AR-PL Registry reveals critical insights into the prevalence and clinical significance of arrhythmic mitral valve prolapse. This study identifies key risk factors associated with the condition, enhancing understanding for future research and treatment strategies.
A case report details mitral valve endocarditis associated with Kodamaea ohmeri, leading to septic embolism in the right femoral artery. This highlights the need for awareness of rare fungal infections in endocarditis cases.