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Mast cell activation syndrome where KIT-mutated and clonal mast cells are detected.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for monoclonal mast cell activation syndrome.
7 publications have been identified in PubMed for monoclonal mast cell activation syndrome. Research spans Review / Meta-Analysis (71%), Basic Science / Preclinical (14%), and Epidemiology / Natural History (14%).
Kepley CL (2025). [PMID: 41317280](https://pubmed.ncbi.nlm.nih.gov/41317280/). *Curr Allergy Asthma Rep*. [Review / Meta-Analysis]
Boggs NA (2025). [PMID: 39187156](https://pubmed.ncbi.nlm.nih.gov/39187156/). *J Allergy Clin Immunol Pract*. [Review / Meta-Analysis]
McMurray JC (2025). [PMID: 40497258](https://pubmed.ncbi.nlm.nih.gov/40497258/). *Front Allergy*. [Review / Meta-Analysis]
Carpio-Escalona LV (2025). [PMID: 40737063](https://pubmed.ncbi.nlm.nih.gov/40737063/). *J Investig Allergol Clin Immunol*. [Review / Meta-Analysis]
Tockova O (2025). [PMID: 40649802](https://pubmed.ncbi.nlm.nih.gov/40649802/). *Int J Mol Sci*. [Basic Science / Preclinical]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 1:32 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Bulai Livideanu C (2025). [PMID: 41039576](https://pubmed.ncbi.nlm.nih.gov/41039576/). *Orphanet J Rare Dis*. [Review / Meta-Analysis]
Degboé Y (2024). [PMID: 38423295](https://pubmed.ncbi.nlm.nih.gov/38423295/). *J Allergy Clin Immunol Pract*. [Epidemiology / Natural History]
AI-curated news mentioning monoclonal mast cell activation syndrome
Updated Jun 4, 2026
New insights into mast cell activation syndrome (MCAS) have emerged with the six-year update on the global consensus-2 diagnostic criteria. This progress aims to enhance diagnostic accuracy and patient management for those affected by this rare condition.