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myeloid neoplasm associated with PDGFRB rearrangement - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

myeloid neoplasm associated with PDGFRB rearrangement

MONDO:0015690

Also known as:myeloid and lymphoid neoplasms with PDGFRB rearrangementmyeloid neoplasms associated with PDGFRB rearrangementmyeloid neoplasms with PDGFRB rearrangement

Overview

A rare, malignant, neoplastic disease characterized by clonal proliferation of myeloid and/or lymphoid precursors harboring rearrangements in the PDGFRB gene, in the blood, bone marrow and often other tissues as well (spleen, lymph nodes, skin, etc.). It usually presents as chronic myelomonocytic leukemia with eosinophilia, chronic eosinophilic leukemia, atypical chronic myelogenous leukemia, juvenile myelomonocytic leukemia, myelodysplastic syndrome, acute myeloid leukemia or acute lymphoblastic leukemia. Patients usually present with anemia, leukocytosis, monocytosis, eosinophilia and/or splenomegaly, or systemic symptoms, such as fever, sweating and/or weight loss.

Diagnosis

Biomarker and diagnostic research for myeloid neoplasm associated with PDGFRB rearrangement has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for myeloid neoplasm associated with PDGFRB rearrangement.

19 publications have been identified in PubMed for myeloid neoplasm associated with PDGFRB rearrangement. Research spans Case Report / Case Series (63%), Review / Meta-Analysis (16%), and Basic Science / Preclinical (16%).

Research Type	Count	% of Total
Patient case studies	12	63%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 11:40 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:168950

GARD

Genetic and Rare Diseases Info Center

GARD:20107

Questions for Your Care Team

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myeloid neoplasm associated with PDGFRB rearrangement

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications