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Neuroleptic malignant syndrome (NMS) is an idiosyncratic condition associated with administration of antipsychotic and other central dopaminergic blockers, and characterized by hyperthermia, muscular rigidity, autonomic dysfunction and altered consciousness.
Biomarker and diagnostic research for neuroleptic malignant syndrome has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for neuroleptic malignant syndrome.
145 publications have been identified in PubMed for neuroleptic malignant syndrome. Kisho has analyzed 107 by research type. Research spans Case Report / Case Series (55%), Review / Meta-Analysis (21%), and Epidemiology / Natural History (11%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 59 | 55% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 9:33 PM UTC
Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries |
22 |
21% |
Disease patterns and progression | 12 | 11% |
Testing and diagnosis research | 4 | 4% |
Laboratory research | 4 | 4% |
Other research | 3 | 3% |
Clinical study results | 3 | 3% |
Sterk B (2026). [PMID: 41542724](https://pubmed.ncbi.nlm.nih.gov/41542724/). *Mov Disord Clin Pract*. [Review / Meta-Analysis]
Ceyran B (2026). [PMID: 41591669](https://pubmed.ncbi.nlm.nih.gov/41591669/). *Cerebellum*. [Case Report / Case Series]
Hochwald EJ (2026). [PMID: 42066041](https://pubmed.ncbi.nlm.nih.gov/42066041/). *J Am Assoc Nurse Pract*. [Case Report / Case Series]
Bitondo MM (2026). [PMID: 42219599](https://pubmed.ncbi.nlm.nih.gov/42219599/). *ASAIO J*. [Case Report / Case Series]
Menon SG (2026). [PMID: 41870353](https://pubmed.ncbi.nlm.nih.gov/41870353/). *J Clin Psychopharmacol*. [Diagnostic / Biomarker]
Sood H (2026). [PMID: 40836881](https://pubmed.ncbi.nlm.nih.gov/40836881/). *Trop Doct*. [Case Report / Case Series]
Ucdal M (2026). [PMID: 42231486](https://pubmed.ncbi.nlm.nih.gov/42231486/). *J Med Case Rep*. [Case Report / Case Series]
El Oumary O (2026). [PMID: 41756567](https://pubmed.ncbi.nlm.nih.gov/41756567/). *Front Psychiatry*. [Case Report / Case Series]
Suekane A (2026). [PMID: 41608809](https://pubmed.ncbi.nlm.nih.gov/41608809/). *Acta Psychiatr Scand*. [Epidemiology / Natural History]
Usta NC (2026). [PMID: 41995787](https://pubmed.ncbi.nlm.nih.gov/41995787/). *Acta Neurol Belg*. [Other]