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A cystic mesothelioma that arises from the peritoneum and usually affects young to middle aged females. Grossly, it presents as a large multiloculated tumor mass, usually in the pelvic peritoneum. Histologically it is characterized by the presence of multiple cysts that are lined by one or more layers of mesothelial cells that do not show atypia. Patients usually present with abdominal or pelvic mass and pain. The clinical course is indolent. The tumor may recur, but transformation to diffuse malignant mesothelioma is rare.
Features include very common findings: Constipation, Abdominal pain, Peritonitis, and Neoplasm and others; and common findings: Menorrhagia, Weight loss, Dyspareunia, and Metrorrhagia.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Digestive system | 3 | Constipation, Abdominal pain, Abdominal distention |
Biomarker and diagnostic research for peritoneal multicystic mesothelioma has been reported in the published literature.
Phenotype severity distribution: 5 very common features, 4 common features.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for peritoneal multicystic mesothelioma.
17 publications have been identified in PubMed for peritoneal multicystic mesothelioma. Research spans Case Report / Case Series (65%), Other (12%), and Diagnostic / Biomarker (6%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 11 | 65% |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:05 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
1 |
Weight loss |
Neoplasm | 1 | Neoplasm |
2 |
12% |
Testing and diagnosis research | 1 | 6% |
Research summaries | 1 | 6% |
Laboratory research | 1 | 6% |
Disease patterns and progression | 1 | 6% |
Aleksandrić G (2026). [PMID: 41523222](https://pubmed.ncbi.nlm.nih.gov/41523222/). *J Surg Case Rep*. [Case Report / Case Series]
Gibson J (2026). [PMID: 41832298](https://pubmed.ncbi.nlm.nih.gov/41832298/). *Br J Cancer*. [Basic Science / Preclinical]
Myers DJ (2026). [PMID: 30285380](https://pubmed.ncbi.nlm.nih.gov/30285380/). *Unknown Journal*. [Other]
Anwar A (2026). [PMID: 32965809](https://pubmed.ncbi.nlm.nih.gov/32965809/). *Unknown Journal*. [Other]
Patil PR (2026). [PMID: 41943495](https://pubmed.ncbi.nlm.nih.gov/41943495/). *Ann Afr Med*. [Diagnostic / Biomarker]
Kitamura Y (2025). [PMID: 41024978](https://pubmed.ncbi.nlm.nih.gov/41024978/). *Surg Case Rep*. [Case Report / Case Series]
Shadmanian A (2025). [PMID: 41295231](https://pubmed.ncbi.nlm.nih.gov/41295231/). *J Pers Med*. [Case Report / Case Series]
Chen Y (2025). [PMID: 40318154](https://pubmed.ncbi.nlm.nih.gov/40318154/). *Int J Gynaecol Obstet*. [Review / Meta-Analysis]
Renavikar PS (2025). [PMID: 40115706](https://pubmed.ncbi.nlm.nih.gov/40115706/). *Cureus*. [Case Report / Case Series]
Aulicino M (2025). [PMID: 40670848](https://pubmed.ncbi.nlm.nih.gov/40670848/). *Ann Surg Oncol*. [Case Report / Case Series]
AI-curated news mentioning peritoneal multicystic mesothelioma
Updated Mar 14, 2026
Recent genomic sequencing of multicystic mesothelioma reveals mutations in the cohesin complex linked to disease recurrence in patients undergoing cytoreductive surgery and HIPEC. This discovery may inform future therapeutic strategies and patient management.