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piriformis syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

piriformis syndrome

MONDO:0043320

Also known as:piriformis muscle syndromePseudosciaticadeep gluteal syndrome

Find Clinical TrialsTrials

Overview

A condition referring to irritation or compression of the proximal sciatic nerve, secondary to contraction of the piriformis muscle. It results in pain in the hip or the back of the leg mimicking disk-related sciatica.

Clinical Trials27 registered · 6 recruiting

Diagnosis

Biomarker and diagnostic research for piriformis syndrome has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

27 clinical trials registered, 6 recruiting. Interventions under study include other interventions, procedural interventions, drug therapy, and medical devices. Pipeline includes 1 PHASE2, 23 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT07044869](https://clinicaltrials.gov/study/NCT07044869)

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:48 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:10026

Questions for Your Care Team

→Are any of the 27 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	7	28%
Research summaries	6	24%
Disease patterns and progression	5	20%
Testing and diagnosis research	3	12%
Clinical study results	2	8%
Other research	1	4%
Laboratory research	1	4%

piriformis syndrome

Overview

Diagnosis

Research Landscape

Medical References

External Resources

GARD

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Questions for Your Care Team

Questions for Your Care Team

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