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polymyalgia rheumatica - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

polymyalgia rheumatica

MONDO:0019735

Also known as:rhizomelic pseudopolyarthritis

Find Clinical TrialsTrials

Overview

A syndrome characterized by pain, stiffness, and tenderness of the proximal muscle groups including the shoulder, pelvic girdle and the neck. There is no muscle atrophy and muscle biopsies do not reveal pathologic changes. Additional signs and symptoms include low grade fever, fatigue and depression.

Treatments1 FDA approved

Clinical Trials28 registered · 14 recruiting

Diagnosis

Biomarker and diagnostic research for polymyalgia rheumatica has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for polymyalgia rheumatica, including SARILUMAB (KEVZARA, approved 2017).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

28 clinical trials registered, 14 recruiting. Interventions under study include other interventions, drug therapy, and biologic therapy. Pipeline includes 4 PHASE4, 5 PHASE3, 2 NA. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT04102930](https://clinicaltrials.gov/study/NCT04102930)

Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 3:33 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:93569

GARD

Genetic and Rare Diseases Info Center

GARD:4704

Questions for Your Care Team

→What are the benefits and potential side effects of KEVZARA for managing polymyalgia rheumatica?
→Are any of the 28 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Research summaries	55	42%
Disease patterns and progression	20	15%
Other research	16	12%
Clinical study results	14	11%
Testing and diagnosis research	9	7%
Laboratory research	9	7%
Patient case studies	7	5%
New treatment approaches	1	1%

polymyalgia rheumatica

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

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