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polyrrhinia - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

polyrrhinia

MONDO:0015388

Also known as:Double nosePolyrhinia

Overview

Polyrrhinia is an extremely rare, major congenital malformation characterized by complete duplication of the nose resulting in twofully developed noses often associated with choanal atresia, causing respiratory distress and necessitating surgical repair.

ResearchLimited published research (1 article)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include common findings: Supernumerary naris, Abnormal external nose morphology, and Abnormal nasal bone morphology; and sometimes findings: Orofacial cleft, Hypertelorism, Abnormality of the glabella, and Abnormal skull base morphology and others.

Organ System	Phenotype Count	Example Features
Bones and joints	1	Abnormal nasal bone morphology

Prognosis

Phenotype severity distribution: 3 common features.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for polyrrhinia.

1 publication has been identified in PubMed for polyrrhinia. Research spans Case Report / Case Series (100%).

Recent Publications

Widarda IR (2024). [PMID: 38631195](https://pubmed.ncbi.nlm.nih.gov/38631195/). *Int J Surg Case Rep*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 8:08 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:141091

GARD

Genetic and Rare Diseases Info Center

GARD:19945

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
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polyrrhinia

Overview

Clinical Presentation

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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