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postherpetic neuralgia - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

postherpetic neuralgia

MONDO:0041052

Also known as:PHN - post-herpetic neuralgiapost-zoster neuralgia

Find Clinical TrialsTrials

Overview

Treatments5 FDA approved

Clinical Trials23 registered · 8 recruiting

Diagnosis

Biomarker and diagnostic research for postherpetic neuralgia has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

3 FDA-approved treatments are available for postherpetic neuralgia, including GABAPENTIN (GRALISE, approved 2011), GABAPENTIN ENACARBIL (HORIZANT, approved 2011), and PREGABALIN (LYRICA CR, approved 2017). An additional 9 compounds hold orphan drug designation.

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

23 clinical trials registered, 8 recruiting. Interventions under study include drug therapy, medical devices, other interventions, and procedural interventions. Pipeline includes 1 PHASE4, 2 PHASE2, 1 PHASE1. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT07256145](https://clinicaltrials.gov/study/NCT07256145)

Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 10:22 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:466673

Questions for Your Care Team

→What are the benefits and potential side effects of GRALISE for managing postherpetic neuralgia?
→Are any of the 23 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Brand Name	Generic Name	Sponsor	Designated	Exclusivity End	Designation Status
d-methadone	d-methadone	Levomecor Inc.	2016	—	Designated
naltrexone/clonidine combination	naltrexone/clonidine combination	Allodynic Therapeutics LLC	2014	—	Designated
1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one	1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one	Zalicus Pharmaceuticals Ltd.	2013	—	Withdrawn
amitriptyline and ketamine	amitriptyline and ketamine	Immune Pharmaceuicals, Inc.	2010	—	Designated
mepivacaine	mepivacaine	Relmada Therapeutics, Inc.	2007	—	Designated
Capsaicin	Capsaicin	TheraQuest Biosciences, LLC	2005	—	Designated
Alfentanil	Alfentanil	Cinergen, LLC	2005	—	Designated
Tramadol hydrochloride	Tramadol hydrochloride	TheraQuest Biosciences, LLC	2005	—	Designated
civamide	civamide	Winston Laboratories, Inc.	2002	—	Designated

Research Type	Count	% of Total
Research summaries	65	38%
Disease patterns and progression	35	20%
Clinical study results	28	16%
Laboratory research	21	12%
New treatment approaches	8	5%
Testing and diagnosis research	7	4%
Patient case studies	6	3%
Other research	2	1%

Kisho

postherpetic neuralgia

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

External Resources

Orphanet

Questions for Your Care Team

Questions for Your Care Team

Orphan Drug Designations

Clinical Trials

Recent Publications

postherpetic neuralgia

Overview

Diagnosis

Treatment

Approved Therapies

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Orphan Drug Designations

Clinical Trials

Recent Publications