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primary oculocerebral lymphoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

primary oculocerebral lymphoma

MONDO:0017205

Also known as:primary oculocerebral non-Hodgkin lymphoma

Overview

Primary oculocerebral lymphoma is a rare, primary, organ-specific, extranodal non-Hodgkin's lymphoma (typically diffuse large B-cell lymphoma), simultaneously affecting the intraocular compartments (retina, vitreous, optic nerve, uvea and others) and the central nervous system (commonly the cerebellum, spinal cord or pia mater). The presenting symptoms vary depending on the localization of the tumor and may include vitreous floaters or blurred vision, raised intracranial pressure (headache, vomiting, papilledema) and/or focal neurological deficits.

ResearchLimited published research (6 articles)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for primary oculocerebral lymphoma.

6 publications have been identified in PubMed for primary oculocerebral lymphoma. Research spans Clinical Trial Publication (50%), Case Report / Case Series (17%), and Basic Science / Preclinical (17%).

Recent Publications

Ahchouch S (2025). [PMID: 40130132](https://pubmed.ncbi.nlm.nih.gov/40130132/). *Cureus*. [Case Report / Case Series]
Liévin R (2025). [PMID: 39394958](https://pubmed.ncbi.nlm.nih.gov/39394958/). *European journal of haematology*. [Clinical Trial Publication]
Hernández-Tost H (2025). [PMID: 40146949](https://pubmed.ncbi.nlm.nih.gov/40146949/). *Neurology*. [Clinical Trial Publication]
Wang L (2025). [PMID: 40078990](https://pubmed.ncbi.nlm.nih.gov/40078990/). *Frontiers in immunology*. [Basic Science / Preclinical]
Mansuy P (2025). [PMID: 41389233](https://pubmed.ncbi.nlm.nih.gov/41389233/). *Journal of ophthalmic inflammation and infection*. [Epidemiology / Natural History]

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 11:12 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:279897

GARD

Genetic and Rare Diseases Info Center

GARD:21062

Questions for Your Care Team

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primary oculocerebral lymphoma

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team