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A rare inflammatory optic neuropathy characterized by recurrent episodes of idiopathic inflammation of the optic nerve head with optic disk edema associated with macular exudate in a star-shaped pattern. Patients present with acute visual loss, most typically in the form of a large central scotoma. Pain is mild or absent. Bilateral involvement is frequent and usually sequential. The interval between attacks is highly variable, ranging from months to several years. Visual loss is cumulative with each attack and often severe.
No clinical trials have been registered for recurrent idiopathic neuroretinitis.
8 publications have been identified in PubMed for recurrent idiopathic neuroretinitis. Research spans Other (25%), Review / Meta-Analysis (25%), and Case Report / Case Series (25%).
Hur M (2026). [PMID: 40528302](https://pubmed.ncbi.nlm.nih.gov/40528302/). *Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society*. [Clinical Trial Publication]
Hur M (2026). [PMID: 41411093](https://pubmed.ncbi.nlm.nih.gov/41411093/). *J Neuroophthalmol*. [Other]
Plant GT (2026). [PMID: 41417464](https://pubmed.ncbi.nlm.nih.gov/41417464/). *J Neuroophthalmol*. [Other]
Arduç-Akçay A (2026). [PMID: 41663981](https://pubmed.ncbi.nlm.nih.gov/41663981/). *BMC Neurol*. [Case Report / Case Series]
Žorić L (2025). [PMID: 39692830](https://pubmed.ncbi.nlm.nih.gov/39692830/). *Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 12:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Jannadi R (2025). [PMID: 40401518](https://pubmed.ncbi.nlm.nih.gov/40401518/). *Ocular immunology and inflammation*. [Epidemiology / Natural History]
Urzedo ABDL (2025). [PMID: 40930735](https://pubmed.ncbi.nlm.nih.gov/40930735/). *BMJ case reports*. [Case Report / Case Series]
Shi J (2025). [PMID: 39537838](https://pubmed.ncbi.nlm.nih.gov/39537838/). *Eye (London, England)*. [Review / Meta-Analysis]