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A category of juvenile idiopathic arthritis defined by the presence of arthritis affecting five or more separate joints during the first six months of disease, with positive serologic testing for rheumatoid factor.
Biomarker and diagnostic research for rheumatoid factor-positive polyarticular juvenile idiopathic arthritis has been reported in the published literature.
Estimated prevalence: 1-9 in 100,000 (Uncommon).
No clinical trials have been registered for rheumatoid factor-positive polyarticular juvenile idiopathic arthritis.
114 publications have been identified in PubMed for rheumatoid factor-positive polyarticular juvenile idiopathic arthritis. Research spans Review / Meta-Analysis (28%), Epidemiology / Natural History (27%), and Basic Science / Preclinical (21%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 32 | 28% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 8:44 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Disease patterns and progression |
31 |
27% |
Laboratory research | 24 | 21% |
Testing and diagnosis research | 14 | 12% |
Clinical study results | 8 | 7% |
Patient case studies | 2 | 2% |
New treatment approaches | 2 | 2% |
Zhou Y (2026). [PMID: 41974575](https://pubmed.ncbi.nlm.nih.gov/41974575/). *Zhejiang Da Xue Xue Bao Yi Xue Ban*. [Epidemiology / Natural History]
Quelain J (2026). [PMID: 41839389](https://pubmed.ncbi.nlm.nih.gov/41839389/). *Presse Med*. [Review / Meta-Analysis]
van Steenbergen HW (2026). [PMID: 40343380](https://pubmed.ncbi.nlm.nih.gov/40343380/). *Arthritis Rheumatol*. [Diagnostic / Biomarker]
Abedeen ZU (2026). [PMID: 41578476](https://pubmed.ncbi.nlm.nih.gov/41578476/). *Medicine (Baltimore)*. [Case Report / Case Series]
Ormsby AL (2026). [PMID: 41354403](https://pubmed.ncbi.nlm.nih.gov/41354403/). *Chest*. [Review / Meta-Analysis]
Öz B (2026). [PMID: 40737101](https://pubmed.ncbi.nlm.nih.gov/40737101/). *Clin Exp Rheumatol*. [Epidemiology / Natural History]
Mahini SM (2026). [PMID: 41483844](https://pubmed.ncbi.nlm.nih.gov/41483844/). *Clin Chim Acta*. [Review / Meta-Analysis]
Cunningham C (2026). [PMID: 41801091](https://pubmed.ncbi.nlm.nih.gov/41801091/). *Arthritis Care Res (Hoboken)*. [Epidemiology / Natural History]
Oshima A (2025). [PMID: 39994731](https://pubmed.ncbi.nlm.nih.gov/39994731/). *Pediatr Rheumatol Online J*. [Epidemiology / Natural History]
Chuang MH (2025). [PMID: 41372709](https://pubmed.ncbi.nlm.nih.gov/41372709/). *Clin Exp Med*. [Basic Science / Preclinical]