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A squamous cell carcinoma arising from the salivary glands. The majority of patients are in their sixth through eight decades. It usually presents as a rapidly enlarging mass, which may be painful. It usually has an aggressive clinical course.
Biomarker and diagnostic research for salivary gland squamous cell carcinoma has been reported in the published literature.
2 clinical trials registered. Interventions under study include drug therapy, other interventions, biologic therapy, and procedural interventions. Pipeline includes 1 PHASE3, 1 PHASE1. Research is primarily sponsored by academic and government institutions.
153 publications have been identified in PubMed for salivary gland squamous cell carcinoma. Research spans Case Report / Case Series (24%), Basic Science / Preclinical (21%), and Review / Meta-Analysis (17%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 37 |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 11:58 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
24%
Laboratory research | 32 | 21% |
Research summaries | 26 | 17% |
Disease patterns and progression | 26 | 17% |
Clinical study results | 17 | 11% |
Testing and diagnosis research | 9 | 6% |
New treatment approaches | 4 | 3% |
Other research | 2 | 1% |
Chu F (2026). [PMID: 41643539](https://pubmed.ncbi.nlm.nih.gov/41643539/). *Oral oncology*. [Epidemiology / Natural History]
Hellquist H (2026). [PMID: 42053816](https://pubmed.ncbi.nlm.nih.gov/42053816/). *Virchows Arch*. [Review / Meta-Analysis]
Giasimakopoulos P (2026). [PMID: 41897631](https://pubmed.ncbi.nlm.nih.gov/41897631/). *Diagnostics (Basel)*. [Review / Meta-Analysis]
Soman D (2026). [PMID: 41544412](https://pubmed.ncbi.nlm.nih.gov/41544412/). *Arch Oral Biol*. [Review / Meta-Analysis]
Su K (2026). [PMID: 41237591](https://pubmed.ncbi.nlm.nih.gov/41237591/). *Int Dent J*. [Basic Science / Preclinical]
Skálová A (2026). [PMID: 42032135](https://pubmed.ncbi.nlm.nih.gov/42032135/). *Virchows Arch*. [Review / Meta-Analysis]
Mayer M (2026). [PMID: 41416670](https://pubmed.ncbi.nlm.nih.gov/41416670/). *Cancer Cytopathol*. [Case Report / Case Series]
Limaiem F (2026). [PMID: 30725962](https://pubmed.ncbi.nlm.nih.gov/30725962/). *Unknown Journal*. [Gene Therapy / Novel Therapeutics]
Young M (2026). [PMID: 34424632](https://pubmed.ncbi.nlm.nih.gov/34424632/). *Unknown Journal*. [Diagnostic / Biomarker]
Kadeeja N (2026). [PMID: 42085019](https://pubmed.ncbi.nlm.nih.gov/42085019/). *Indian J Pathol Microbiol*. [Case Report / Case Series]
AI-curated news mentioning salivary gland squamous cell carcinoma
Updated May 5, 2026
A study identifies a rare variant in the LAMP3 gene that enhances epithelial cell apoptosis, leading to salivary gland dysfunction. This discovery could inform future research on therapies targeting this genetic variant.