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Schistosomiasis — NIH Grants & Funding

Active and recent NIH-funded research on Schistosomiasis. Data from NIH RePORTER, last 36 months.

MONDO:0015254

NIH-funded research on Schistosomiasis

active grants

institutions

researchers

new in last 12 mo.

$55.0M in NIH funding over the last 36 months. Data from NIH RePORTER.

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Basic Science(18)

Basic ScienceR01Active

Genetics and genomics of schistosome resistance in snails

ZHANG, SI-MING·UNIVERSITY OF NEW MEXICO·ALBUQUERQUE, NM

$1,077,146 (FY2025)

Schistosomiasis — NIH Grants & Funding

Basic Science(18)

Genetics and genomics of schistosome resistance in snails

Resolving the properties of schistosome TRPMPZQ, the target of the anthelmintic drug praziquantel

STING-Dependent Pathways Restraining Severe Schistosome Immunopathology

Functional Characterization of the Schistosome Tegument

Genetic mechanisms of snail/schistosome compatibility

Molecular Determinants and Behavioral Fingerprints of Schistosome Miracidia Host-Seeking

An RCT to Evaluate Treatment Modalities to Halt the Progression of Schistosomiasis Related Hepatic Fibrosis

The contribution of hypoxia inducible factor-1-dependent glycolysis in lung interstitial macrophages to the pathobiology of schistosomiasis-induced pulmonary hypertension.

Activation, Phenotype and Function of CD4 T Cells in Schistosoma-Pulmonary Hypertension

Vitamin A Status and its Relationship to S. mansoni Infection Intensity and Environmental Enteric Dysfunction in Preschool-Aged Children Receiving Treatment for Schistosomiasis in Uganda

Translational(15)

Drug Target Discovery, Validation, and Prioritization for Schistosomiasis

Development of novel TGR inhibitors for the treatment of schistosomiasis

Refining Predictive Models for Neglected and Emerging Infectious Diseases

Discovery and development of novel schistosomicidal agents

Preclinical Testing of Potential Next-generation Antischistosomal Compounds

Identification of novel anthelmintics through a target-based screen of a parasite ion channel

A Vaccine for Schistosomiasis, "SchistoShield"

The Biology of Stem Cells in the Human Parasite Schistosoma Mansoni

Evaluation of a Next Generation SchistoShield Vaccine

Enhancing detection and mobile monitoring of schistosomiasis with urine-based analyte pre-concentration technology

Clinical(8)

Genital Immune, Mucosal, and Viral Effects of Female Genital Schistosomiasis in Tanzania

Snail-Related Studies of Transmission & Control of Schistosomiasis in Kenya

An RCT to Evaluate Treatment Modalities to Halt the Progression of Schistosomiasis Related Hepatic Fibrosis

Schistosomiasis and Women's Reproductive Health

Optimization of Antischistosomal Chemotypes

Phase II PK/PD driven dose finding trial of Praziquantel in children under four

Clinical and immunological impact of Schistosoma mansoni infection and treatment on the course of chronic hepatitis B virus (HBV) infection in Uganda

Schistosoma Mansoni Infection During Pregnancy: Dissecting the Implications to Fetal Immunity

Epi / Nat. History(8)

Precision mapping of Schistosoma mansoni risk for targeted public health control and elimination

Uganda Schistosomiasis Multidisciplinary Research Centre (U-SMRC)

Esophageal gland-mediated immune evasion by the human parasite Schistosoma mansoni

Identifying schistosomiasis resistance genes of snail vectors in hotspot transmission zones: Translating from laboratory models to the field.

Resource competition drives natural and rebound dynamics of snails and schistosomes

Optimizing interventions to mitigate schistosomiasis-related morbidity among pregnant women and children

Performance of the pooled testing strategy for detecting and estimating the prevalence and intensity of Schistosoma haematobium infection at a population level

Predicting the success of biological control for snail vectors of human schistosomiaisis

Gene/Cell Therapy(1)

Oncolytic virus targeting Schistosomes

Biomarker / Dx(2)

Biomarkers to Identify Individuals at RIsk for Progression of S. Japonicum Associated Hepatic Fibrosis with Point of Care Test Development

Screening for schistosomiasis-associated pulmonary arterial hypertension

Medical Device(1)

Fine-resolution genetic mapping of advanced intercross lines of Biomphalaria glabrata

Other(3)

Microscale Multiplexed Antibody Fc Profiling and Nanoscale Electronic Detection for Rapid and Scalable Point-of-Care Diagnosis of Tuberculosis

Antigen and adjuvant selection for a vaccine against urogenital schistosomiasis, Hematoshield

Building capacity for Global Infectious Disease Research Training in Schistosomiasis in sub-Saharan Africa