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selective IgE deficiency disease - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

selective IgE deficiency disease

MONDO:0003738

Also known as:selective IgE immunodeficiencyselective immunoglobulin E deficiency

Overview

A rare dysgammaglobulinemia characterized by low or undetectable serum levels of immunoglobulin class E (IgE). It is an uncommon primary antibody deficiency. It is most likely an inherited immunodeficiency. It may be caused by decreased or inefficient class-switching from progenitor B cells without any corresponding decreases in the other isotypes. Most affected persons appear asymptomatic but may show a predisposition to autoimmune and respiratory diseases.

Diagnosis

Biomarker and diagnostic research for selective IgE deficiency disease has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for selective IgE deficiency disease.

32 publications have been identified in PubMed for selective IgE deficiency disease. Research spans Review / Meta-Analysis (41%), Epidemiology / Natural History (21%), and Diagnostic / Biomarker (14%).

Research Type	Count	% of Total
Research summaries	12	41%

Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 7:49 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

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selective IgE deficiency disease

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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