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selective IgG immunodeficiency - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

selective IgG immunodeficiency

MONDO:0045045

Also known as:IgG deficiencyIgG subclass deficiency

Overview

A broad classification of dysgammaglobulinemias characterized by low or undetectable serum levels of immunoglobulin class G (IgG). Deficiencies of IgG present variably according to subclass. IgG deficiencies are typically relative among subclasses and not absolute. Thus even with a given selective IgG subclass deficiency, total IgG levels may still fall within normal range. The clinical course and prognosis is dependent upon the severity of the deficiency and associated morbidity.

Diagnosis

Biomarker and diagnostic research for selective IgG immunodeficiency has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for selective IgG immunodeficiency.

227 publications have been identified in PubMed for selective IgG immunodeficiency. Research spans Basic Science / Preclinical (30%), Epidemiology / Natural History (19%), and Review / Meta-Analysis (18%).

Research Type	Count	% of Total
Laboratory research	67	30%

Data assembled from 2 of 12 sources · Last updated Sep 18, 2026, 7:47 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

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selective IgG immunodeficiency

Overview

Diagnosis

Research Landscape

Medical References

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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