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A childhood-onset self-limited focal epilepsy syndrome characterized by the onset in early childhood of focal autonomic seizures that are often prolonged. The EEG commonly shows high amplitude focal spikes typically activated by sleep. Seizures are infrequent in most patients. Seizures are self-limiting with remission typically within a few years from onset.
Biomarker and diagnostic research for self-limited epilepsy with autonomic seizures has been reported in the published literature.
No clinical trials have been registered for self-limited epilepsy with autonomic seizures.
12 publications have been identified in PubMed for self-limited epilepsy with autonomic seizures. Research spans Case Report / Case Series (58%), Basic Science / Preclinical (33%), and Diagnostic / Biomarker (8%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 7 | 58% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:41 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Laboratory research
4 |
33% |
Testing and diagnosis research | 1 | 8% |
Tekin HG (2026). [PMID: 41489379](https://pubmed.ncbi.nlm.nih.gov/41489379/). *Epileptic disorders : international epilepsy journal with videotape*. [Diagnostic / Biomarker]
Kesavamoorthy N (2026). [PMID: 41704823](https://pubmed.ncbi.nlm.nih.gov/41704823/). *Case reports in neurological medicine*. [Case Report / Case Series]
Tomori S (2026). [PMID: 41642419](https://pubmed.ncbi.nlm.nih.gov/41642419/). *CEN case reports*. [Case Report / Case Series]
İriş M (2026). [PMID: 41570778](https://pubmed.ncbi.nlm.nih.gov/41570778/). *Seizure*. [Basic Science / Preclinical]
Emmady PD (2026). [PMID: 32491402](https://pubmed.ncbi.nlm.nih.gov/32491402/). *Unknown Journal*. [Case Report / Case Series]
Tekin HG (2025). [PMID: 39904222](https://pubmed.ncbi.nlm.nih.gov/39904222/). *Brain & development*. [Basic Science / Preclinical]
Itamura S (2025). [PMID: 40905610](https://pubmed.ncbi.nlm.nih.gov/40905610/). *Pediatrics international : official journal of the Japan Pediatric Society*. [Case Report / Case Series]
Balaram N (2025). [PMID: 40485226](https://pubmed.ncbi.nlm.nih.gov/40485226/). *Annals of Indian Academy of Neurology*. [Basic Science / Preclinical]
Giliberti A (2025). [PMID: 40394668](https://pubmed.ncbi.nlm.nih.gov/40394668/). *Italian journal of pediatrics*. [Case Report / Case Series]
Felgueiras A (2024). [PMID: 39246861](https://pubmed.ncbi.nlm.nih.gov/39246861/). *Cureus*. [Case Report / Case Series]