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A soft tissue neoplasm composed of acellular amyloid material.
Biomarker and diagnostic research for soft tissue amyloid neoplasm has been reported in the published literature.
No approved treatments are currently available for soft tissue amyloid neoplasm. An additional 1 compound holds orphan drug designation.
While no drugs are FDA-approved specifically for soft tissue amyloid neoplasm, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.
The following drugs have received orphan drug designation from the FDA for soft tissue amyloid neoplasm. Orphan designation reflects regulatory interest and does not indicate approval for treatment.
Brand Name | Generic Name | Sponsor |
|---|
No clinical trials have been registered for soft tissue amyloid neoplasm.
111 publications have been identified in PubMed for soft tissue amyloid neoplasm. Research spans Basic Science / Preclinical (37%), Review / Meta-Analysis (32%), and Case Report / Case Series (12%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 41 | 37% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 9:52 AM UTC
Designated
Exclusivity End |
|---|
Designation Status |
|---|
ifosfamide | ifosfamide | Bristol-Myers Squibb Company | 1985 | — | Designated |
Gene therapy approaches for soft tissue amyloid neoplasm have been reported in the published literature.
View trials for soft tissue amyloid neoplasm
35 |
32% |
Patient case studies | 13 | 12% |
Testing and diagnosis research | 7 | 6% |
Disease patterns and progression | 6 | 5% |
Clinical study results | 4 | 4% |
New treatment approaches | 4 | 4% |
Other research | 1 | 1% |
Ling J (2026). [PMID: 41894688](https://pubmed.ncbi.nlm.nih.gov/41894688/). *Blood Adv*. [Review / Meta-Analysis]
Karpinski MJ (2026). [PMID: 41819113](https://pubmed.ncbi.nlm.nih.gov/41819113/). *Lancet Oncol*. [Epidemiology / Natural History]
Ramos Cardona JC (2026). [PMID: 42147100](https://pubmed.ncbi.nlm.nih.gov/42147100/). *Front Endocrinol (Lausanne)*. [Case Report / Case Series]
Almukhlifi A (2025). [PMID: 40376382](https://pubmed.ncbi.nlm.nih.gov/40376382/). *Cureus*. [Case Report / Case Series]
Özdemir AY (2025). [PMID: 40359691](https://pubmed.ncbi.nlm.nih.gov/40359691/). *Biomed Pharmacother*. [Basic Science / Preclinical]
Benz DC (2025). [PMID: 40938234](https://pubmed.ncbi.nlm.nih.gov/40938234/). *JACC Cardiovasc Imaging*. [Clinical Trial Publication]
Zhang W (2025). [PMID: 40545028](https://pubmed.ncbi.nlm.nih.gov/40545028/). *Drug Discov Today*. [Review / Meta-Analysis]
Yu C (2025). [PMID: 41402326](https://pubmed.ncbi.nlm.nih.gov/41402326/). *Nat Commun*. [Epidemiology / Natural History]
Baschong A (2025). [PMID: 41100818](https://pubmed.ncbi.nlm.nih.gov/41100818/). *Swiss Med Wkly*. [Case Report / Case Series]
Dorbala S (2025). [PMID: 39985507](https://pubmed.ncbi.nlm.nih.gov/39985507/). *JACC Cardiovasc Imaging*. [Review / Meta-Analysis]
AI-curated news mentioning soft tissue amyloid neoplasm
Updated Apr 13, 2026
A recent study published in PubMed investigates the malignancy rates of synovially-based soft tissue lesions in the knee. The findings contribute to understanding the clinical implications of these lesions in patient management.