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Solitary fibrous tumor (SFT) represents a diverse group of ubiquitous rare spindle cell neoplasms that may be benign or malignant and that most frequently arises from the pleura and peritoneum and rarely from other sites such as head and neck, liver and skeletal muscle. SFT may be clinically asymptomatic or may present with enlarging mass, compressive effects depending on the site involved and rarely with paraneoplastic manifestations (osteoarthropathy or hypoglycemia).
Biomarker and diagnostic research for solitary fibrous tumor has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
5 clinical trials registered, 2 recruiting. Interventions under study include other interventions, drug therapy, and procedural interventions. Pipeline includes 2 PHASE1, 1 NA. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05259605](https://clinicaltrials.gov/study/NCT05259605) |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 5:31 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification |
— |
European Organisation for Research and Treatment of Cancer - EORTC |
UNKNOWN |
[NCT03967834](https://clinicaltrials.gov/study/NCT03967834) | Multimodal Immune Characterization of RAre Soft Tissue Sarcoma - MIRAS Project From SARRA (SARcome RAre) Project of the French Sarcoma Group | NA | Institut Claudius Regaud | RECRUITING |
[NCT06789172](https://clinicaltrials.gov/study/NCT06789172) | A Phase 1, First-in-human Study of OKN4395 and Pembrolizumab in Patients With Solid Tumors | PHASE1 | Epkin | UNKNOWN |
[NCT07118176](https://clinicaltrials.gov/study/NCT07118176) | Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic Cancers | PHASE1 | Jonsson Comprehensive Cancer Center | ACTIVE_NOT_RECRUITING |
[NCT04648462](https://clinicaltrials.gov/study/NCT04648462) | Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology | — | Maastricht Radiation Oncology | RECRUITING |
247 publications have been identified in PubMed for solitary fibrous tumor. Research spans Case Report / Case Series (63%), Review / Meta-Analysis (12%), and Diagnostic / Biomarker (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 156 | 63% |
Research summaries | 29 | 12% |
Testing and diagnosis research | 23 | 9% |
Laboratory research | 13 | 5% |
Clinical study results | 10 | 4% |
Disease patterns and progression | 9 | 4% |
Other research | 5 | 2% |
New treatment approaches | 2 | 1% |
Soriano Palao MT (2026). [PMID: 41881771](https://pubmed.ncbi.nlm.nih.gov/41881771/). *Endocrinol Diabetes Nutr (Engl Ed)*. [Review / Meta-Analysis]
Kalita P (2026). [PMID: 41726024](https://pubmed.ncbi.nlm.nih.gov/41726024/). *Indian J Surg Oncol*. [Diagnostic / Biomarker]
Tos SM (2026). [PMID: 41592232](https://pubmed.ncbi.nlm.nih.gov/41592232/). *Neuro Oncol*. [Clinical Trial Publication]
Narimatsu R (2026). [PMID: 41503433](https://pubmed.ncbi.nlm.nih.gov/41503433/). *IJU Case Rep*. [Case Report / Case Series]
Pando A (2026). [PMID: 41896408](https://pubmed.ncbi.nlm.nih.gov/41896408/). *Acta Neurochir (Wien)*. [Diagnostic / Biomarker]
Suetsugu H (2026). [PMID: 41941841](https://pubmed.ncbi.nlm.nih.gov/41941841/). *J Neurosurg Case Lessons*. [Case Report / Case Series]
Choi JH (2026). [PMID: 41531321](https://pubmed.ncbi.nlm.nih.gov/41531321/). *Journal of pathology and translational medicine*. [Case Report / Case Series]
Li Y (2026). [PMID: 42176797](https://pubmed.ncbi.nlm.nih.gov/42176797/). *Cancer Lett*. [Basic Science / Preclinical]
Alabdulrazaq ES (2026). [PMID: 37983342](https://pubmed.ncbi.nlm.nih.gov/37983342/). *Unknown Journal*. [Case Report / Case Series]
Gao W (2026). [PMID: 42155214](https://pubmed.ncbi.nlm.nih.gov/42155214/). *Pathol Res Pract*. [Epidemiology / Natural History]
AI-curated news mentioning solitary fibrous tumor
Updated Aug 29, 2026
A multi-institutional study reviewed 33 cases of solitary fibrous tumors in the prostate and periprostatic region, contributing valuable insights to the understanding of this rare tumor type. The findings may help inform future research and clinical approaches.
A rare case study highlights a solitary fibrous tumor originating from the uterine corpus in a patient with Doege-Potter syndrome, presenting recurrent disease without hypoglycemia. This case contributes to the understanding of the tumor's behavior in the context of this rare syndrome.
Recent research published in PubMed explores systemic therapy options for solitary fibrous tumors, highlighting potential treatment pathways. This study contributes to the understanding of therapeutic strategies for this rare tumor type.