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Systemic mastocytosis with an associated clonal hematological non-mast cell lineage disease is a form of systemic mastocytosis (SM) associated with malignancy (other than mast cell leukemia).
Biomarker and diagnostic research for systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease has been reported in the published literature.
Estimated prevalence: 1-9 in 100,000 (Uncommon).
1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy. Pipeline includes 1 PHASE2. Research is primarily industry-sponsored.
21 publications have been identified in PubMed for systemic mastocytosis with an associated clonal hematologic non-mast cell lineage disease. Research spans Case Report / Case Series (29%), Review / Meta-Analysis (19%), and Clinical Trial Publication (19%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 6 | 29% |
Research summaries | 4 | 19% |
Clinical study results | 4 | 19% |
Testing and diagnosis research | 3 | 14% |
Disease patterns and progression | 2 | 10% |
Other research | 1 | 5% |
New treatment approaches | 1 | 5% |
Zhao Y (2026). [PMID: 40938150](https://pubmed.ncbi.nlm.nih.gov/40938150/). *Clinical nuclear medicine*. [Case Report / Case Series]
Gotlib J (2026). [PMID: 41604606](https://pubmed.ncbi.nlm.nih.gov/41604606/). *Blood advances*. [Clinical Trial Publication]
Reiter A (2026). [PMID: 41187902](https://pubmed.ncbi.nlm.nih.gov/41187902/). *The journal of allergy and clinical immunology. In practice*. [Other]
Ecker V (2025). [PMID: 40256960](https://pubmed.ncbi.nlm.nih.gov/40256960/). *Current protocols*. [Case Report / Case Series]
Aperna F (2025). [PMID: 40607735](https://pubmed.ncbi.nlm.nih.gov/40607735/). *American journal of hematology*. [Review / Meta-Analysis]
John MV (2025). [PMID: 40913208](https://pubmed.ncbi.nlm.nih.gov/40913208/). *Annals of hematology*. [Case Report / Case Series]
Dranitsaris G (2025). [PMID: 38151028](https://pubmed.ncbi.nlm.nih.gov/38151028/). *Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners*. [Diagnostic / Biomarker]
Ustun C (2025). [PMID: 40983528](https://pubmed.ncbi.nlm.nih.gov/40983528/). *British journal of haematology*. [Epidemiology / Natural History]
Radia DH (2025). [PMID: 39808818](https://pubmed.ncbi.nlm.nih.gov/39808818/). *Blood*. [Review / Meta-Analysis]
Soare D (2025). [PMID: 40893810](https://pubmed.ncbi.nlm.nih.gov/40893810/). *Journal of medicine and life*. [Epidemiology / Natural History]
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:41 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center