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An acute T-lymphoblastic leukemia occurring in adults.
Biomarker and diagnostic research for T-cell adult acute lymphocytic leukemia has been reported in the published literature.
11 clinical trials registered, 4 recruiting. Interventions under study include drug therapy, procedural interventions, other interventions, and medical devices. Pipeline includes 1 PHASE3, 5 PHASE2, 1 PHASE1. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT01137825](https://clinicaltrials.gov/study/NCT01137825) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:34 PM UTC
Registry of Older Patients With Cancer |
— |
UNC Lineberger Comprehensive Cancer Center |
RECRUITING |
[NCT01137643](https://clinicaltrials.gov/study/NCT01137643) | Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer | — | UNC Lineberger Comprehensive Cancer Center | RECRUITING |
[NCT06698003](https://clinicaltrials.gov/study/NCT06698003) | A Study of Mogamulizumab to Prevent Adult T-cell Leukemia/Lymphoma in People With HTLV-1 | PHASE2 | Memorial Sloan Kettering Cancer Center | RECRUITING |
[NCT05031897](https://clinicaltrials.gov/study/NCT05031897) | Two Step Haplo With Radiation Conditioning | PHASE2 | Thomas Jefferson University | RECRUITING |
318 publications have been identified in PubMed for T-cell adult acute lymphocytic leukemia. Kisho has analyzed 82 by research type. Research spans Clinical Trial Publication (38%), Review / Meta-Analysis (32%), and Basic Science / Preclinical (11%).
Research Type | Count | % of Total |
|---|---|---|
Clinical study results | 31 | 38% |
Research summaries | 26 | 32% |
Laboratory research | 9 | 11% |
Disease patterns and progression | 7 | 9% |
Testing and diagnosis research | 3 | 4% |
Patient case studies | 3 | 4% |
New treatment approaches | 2 | 2% |
Other research | 1 | 1% |
Chiesa R (2026). [PMID: 41363805](https://pubmed.ncbi.nlm.nih.gov/41363805/). *N Engl J Med*. [Clinical Trial Publication]
Te Vrugt M (2025). [PMID: 40808247](https://pubmed.ncbi.nlm.nih.gov/40808247/). *Br J Haematol*. [Review / Meta-Analysis]
Luskin MR (2025). [PMID: 39546748](https://pubmed.ncbi.nlm.nih.gov/39546748/). *Blood Adv*. [Clinical Trial Publication]
Dulery R (2025). [PMID: 39779930](https://pubmed.ncbi.nlm.nih.gov/39779930/). *Nat Med*. [Epidemiology / Natural History]
Adomako J (2025). [PMID: 40413101](https://pubmed.ncbi.nlm.nih.gov/40413101/). *Trends Mol Med*. [Review / Meta-Analysis]
E S (2025). [PMID: 40318961](https://pubmed.ncbi.nlm.nih.gov/40318961/). *Pathology*. [Basic Science / Preclinical]
Kantarjian H (2025). [PMID: 40759141](https://pubmed.ncbi.nlm.nih.gov/40759141/). *Lancet*. [Review / Meta-Analysis]
Summers RJ (2025). [PMID: 38364183](https://pubmed.ncbi.nlm.nih.gov/38364183/). *Blood*. [Review / Meta-Analysis]
Zhang M (2025). [PMID: 40244598](https://pubmed.ncbi.nlm.nih.gov/40244598/). *JAMA Oncol*. [Clinical Trial Publication]
Xu J (2025). [PMID: 41348046](https://pubmed.ncbi.nlm.nih.gov/41348046/). *Hematology Am Soc Hematol Educ Program*. [Review / Meta-Analysis]
AI-curated news mentioning T-cell adult acute lymphocytic leukemia
Updated Sep 10, 2026
A recent study compares the outcomes of CHOP versus CHOEP/EPOCH regimens in treating aggressive adult T-cell leukemia/lymphoma. The international cohort analysis provides insights that could influence treatment protocols for this rare disease.
A recent study published in PubMed highlights the prognostic significance of morphological lymphocyte counts in aggressive adult T-cell leukemia/lymphoma. This analysis utilized data from the Japan ATL nationwide registry, providing insights that could influence future treatment strategies.
Recent research highlights the importance of targeted maternal screening for adult T-cell leukemia/lymphoma. This study aims to improve early detection and management of the disease.