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An adenocarcinoma arising from the vagina. Morphologic variants include the clear cell, endometrioid, mesonephric, and mucinous adenocarcinoma.
Biomarker and diagnostic research for vaginal adenocarcinoma has been reported in the published literature.
6 clinical trials registered, 1 recruiting. Interventions under study include biologic therapy, drug therapy, procedural interventions, and other interventions. Pipeline includes 1 PHASE3, 3 PHASE2, 2 PHASE1. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT05686226](https://clinicaltrials.gov/study/NCT05686226) |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 6:47 AM UTC
E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers |
PHASE2 |
Christian Hinrichs |
RECRUITING |
[NCT06730347](https://clinicaltrials.gov/study/NCT06730347) | A Study of Lorigerlimab in Participants With Advanced Solid Tumors | PHASE2 | MacroGenics | UNKNOWN |
[NCT02834013](https://clinicaltrials.gov/study/NCT02834013) | Nivolumab and Ipilimumab in Treating Patients With Rare Tumors | PHASE2 | National Cancer Institute (NCI) | ACTIVE_NOT_RECRUITING |
[NCT05973487](https://clinicaltrials.gov/study/NCT05973487) | A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors | PHASE1 | TScan Therapeutics, Inc. | ACTIVE_NOT_RECRUITING |
[NCT02595879](https://clinicaltrials.gov/study/NCT02595879) | Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer | PHASE1 | National Cancer Institute (NCI) | ACTIVE_NOT_RECRUITING |
73 publications have been identified in PubMed for vaginal adenocarcinoma. Research spans Case Report / Case Series (56%), Review / Meta-Analysis (19%), and Basic Science / Preclinical (8%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 41 | 56% |
Research summaries | 14 | 19% |
Laboratory research | 6 | 8% |
Disease patterns and progression | 6 | 8% |
Clinical study results | 3 | 4% |
Testing and diagnosis research | 2 | 3% |
Other research | 1 | 1% |
Parisi G (2026). [PMID: 42074625](https://pubmed.ncbi.nlm.nih.gov/42074625/). *J Clin Med*. [Review / Meta-Analysis]
Murray J (2026). [PMID: 42021387](https://pubmed.ncbi.nlm.nih.gov/42021387/). *Cell Biosci*. [Basic Science / Preclinical]
Wong RW (2026). [PMID: 42023432](https://pubmed.ncbi.nlm.nih.gov/42023432/). *Histopathology*. [Review / Meta-Analysis]
Yuan M (2026). [PMID: 42088196](https://pubmed.ncbi.nlm.nih.gov/42088196/). *Front Oncol*. [Case Report / Case Series]
Aguiar RS (2026). [PMID: 42173533](https://pubmed.ncbi.nlm.nih.gov/42173533/). *BMJ Case Rep*. [Case Report / Case Series]
Chae YK (2026). [PMID: 41995270](https://pubmed.ncbi.nlm.nih.gov/41995270/). *J Gynecol Oncol*. [Clinical Trial Publication]
Halder S (2026). [PMID: 41834193](https://pubmed.ncbi.nlm.nih.gov/41834193/). *The journal of obstetrics and gynaecology research*. [Case Report / Case Series]
Seow-En I (2026). [PMID: 42000922](https://pubmed.ncbi.nlm.nih.gov/42000922/). *Tech Coloproctol*. [Other]
Saab R (2026). [PMID: 41650791](https://pubmed.ncbi.nlm.nih.gov/41650791/). *Gynecologic oncology*. [Review / Meta-Analysis]
Wang T (2026). [PMID: 42205203](https://pubmed.ncbi.nlm.nih.gov/42205203/). *Oncol Lett*. [Case Report / Case Series]