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An acute arboviral infection caused by an alphavirus of the Togaviridae family transmitted by an infected mosquito, that more frequently affects children and that is characterized by the presence of mild flulike symptoms (fever, chills, headache, nausea, vomiting, and anorexia) but that can progress to weakness, altered mental status, photophobia, mental confusion, seizures, somnolence, coma and/or even death. The disease can leave neurological sequelae, mainly in infants and children, such as seizures, spasticity or behavioral disorders.
Biomarker and diagnostic research for western equine encephalitis has been reported in the published literature.
Estimated prevalence: 1-9 in 1,000,000 (Rare).
No clinical trials have been registered for western equine encephalitis.
52 publications have been identified in PubMed for western equine encephalitis. Research spans Basic Science / Preclinical (46%), Epidemiology / Natural History (17%), and Review / Meta-Analysis (12%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 24 | 46% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:24 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
9 |
17% |
Research summaries | 6 | 12% |
New treatment approaches | 5 | 10% |
Testing and diagnosis research | 3 | 6% |
Patient case studies | 3 | 6% |
Other research | 2 | 4% |
Dhawan S (2026). [PMID: 41480662](https://pubmed.ncbi.nlm.nih.gov/41480662/). *Epidemiol Infect*. [Review / Meta-Analysis]
Hayashi DJ (2026). [PMID: 41849539](https://pubmed.ncbi.nlm.nih.gov/41849539/). *Mem Inst Oswaldo Cruz*. [Epidemiology / Natural History]
Cui Y (2026). [PMID: 42020326](https://pubmed.ncbi.nlm.nih.gov/42020326/). *Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi*. [Diagnostic / Biomarker]
Rock ML (2026). [PMID: 41161420](https://pubmed.ncbi.nlm.nih.gov/41161420/). *J Virol Methods*. [Basic Science / Preclinical]
Wong J (2026). [PMID: 41537597](https://pubmed.ncbi.nlm.nih.gov/41537597/). *J Virol*. [Basic Science / Preclinical]
Ward HM (2026). [PMID: 42075733](https://pubmed.ncbi.nlm.nih.gov/42075733/). *Pathogens*. [Diagnostic / Biomarker]
Yang X (2026). [PMID: 42004740](https://pubmed.ncbi.nlm.nih.gov/42004740/). *Infect Med (Beijing)*. [Review / Meta-Analysis]
Lukash T (2026). [PMID: 41662398](https://pubmed.ncbi.nlm.nih.gov/41662398/). *PLoS Pathog*. [Gene Therapy / Novel Therapeutics]
Wang L (2025). [PMID: 41178425](https://pubmed.ncbi.nlm.nih.gov/41178425/). *Virulence*. [Review / Meta-Analysis]
Liu Y (2025). [PMID: 40890032](https://pubmed.ncbi.nlm.nih.gov/40890032/). *Emerg Microbes Infect*. [Basic Science / Preclinical]