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An endemic, infectious, nonvenereal disease in humans that presents mainly in children younger than 15 years. The disease occurs primarily in warm, humid, tropical areas of Africa, Asia, South America, and Oceania, among poor rural populations where conditions of overcrowding and poor sanitation prevail. Infection with Treponema pertenue, a subspecies of Treponema pallidum, causes the disease.
Biomarker and diagnostic research for yaws has been reported in the published literature.
No clinical trials have been registered for yaws.
198 publications have been identified in PubMed for yaws. Kisho has analyzed 90 by research type. Research spans Epidemiology / Natural History (28%), Review / Meta-Analysis (27%), and Basic Science / Preclinical (17%).
Research Type | Count | % of Total |
|---|---|---|
Disease patterns and progression | 25 | 28% |
Data assembled from 2 of 12 sources · Last updated Sep 19, 2026, 9:37 PM UTC
Genetic and Rare Diseases Info Center
Research summaries
24 |
27% |
Laboratory research | 15 | 17% |
Clinical study results | 10 | 11% |
Testing and diagnosis research | 7 | 8% |
Patient case studies | 5 | 6% |
Other research | 3 | 3% |
New treatment approaches | 1 | 1% |
Agbanyo A (2026). [PMID: 41911295](https://pubmed.ncbi.nlm.nih.gov/41911295/). *PLoS Negl Trop Dis*. [Clinical Trial Publication]
Putri AZ (2026). [PMID: 42188852](https://pubmed.ncbi.nlm.nih.gov/42188852/). *Trop Med Infect Dis*. [Review / Meta-Analysis]
Kostoulas C (2026). [PMID: 42212615](https://pubmed.ncbi.nlm.nih.gov/42212615/). *Am J Med Genet A*. [Epidemiology / Natural History]
Fokam J (2026). [PMID: 41265787](https://pubmed.ncbi.nlm.nih.gov/41265787/). *J Mol Diagn*. [Epidemiology / Natural History]
Lewis DA (2026). [PMID: 41046959](https://pubmed.ncbi.nlm.nih.gov/41046959/). *Clin Dermatol*. [Review / Meta-Analysis]
Atsama-Amougou M (2026). [PMID: 42044180](https://pubmed.ncbi.nlm.nih.gov/42044180/). *PLoS One*. [Diagnostic / Biomarker]
Brothwell JA (2026). [PMID: 41738753](https://pubmed.ncbi.nlm.nih.gov/41738753/). *mSphere*. [Epidemiology / Natural History]
Unknown (2026). [PMID: 42133785](https://pubmed.ncbi.nlm.nih.gov/42133785/). *Science*. [Other]
Bouba Y (2026). [PMID: 42139226](https://pubmed.ncbi.nlm.nih.gov/42139226/). *PLOS Glob Public Health*. [Epidemiology / Natural History]
Anwar S (2026). [PMID: 42149907](https://pubmed.ncbi.nlm.nih.gov/42149907/). *PLoS Negl Trop Dis*. [Epidemiology / Natural History]