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Plain-language summaries of 10,888 rare conditions, drawn from MONDO, GeneReviews, ClinVar, FDA, NIH, ClinicalTrials.gov, PubMed, and 5 other public sources. Free, sourced, never gated.
Kisho provides public health information only — not medical advice. Always consult your healthcare provider.
12
authoritative sources — clinical, regulatory, scientific
10,888
rare conditions, continuously monitored
Daily
updates from MONDO, HPO, ClinicalTrials.gov, FDA, Orphanet…
Showing 6,941-6,960 of 10,888 diseases
MONDO:0012334
Hereditary spastic paraplegia type 29, also known as SPG29, is a complex neurological condition that primarily affects the motor system. It is charact...
MONDO:0012476
Hereditary spastic paraplegia 30 is a neurologic condition that primarily affects the lower limbs and is characterized by spasticity, unsteady gait, a...
MONDO:0012453
MONDO:0012643
MONDO:0012448
MONDO:0010418
Hereditary spastic paraplegia 34 is an X‐linked neurological condition characterized by a slowly progressive spastic paraplegia that typically begins...
MONDO:0012866
Hereditary spastic paraplegia 35 is a rare neurological condition that primarily affects the motor pathways, leading to spasticity and gait abnormalit...
MONDO:0013132
MONDO:0012766
Hereditary spastic paraplegia 37 is a pure form of hereditary spastic paraplegia that primarily affects the motor pathways, leading to slowly progress...
MONDO:0012867
Hereditary spastic paraplegia 38 (also known as SPG38 or autosomal dominant spastic paraplegia type 38) is an inherited disorder that primarily affect...
MONDO:0012787
Hereditary spastic paraplegia 39 is a neurological disorder primarily affecting the motor system, manifesting as progressive stiffness and weakness in...
MONDO:0008437
Hereditary spastic paraplegia 3A is an inherited neurological disorder that primarily affects the motor system, leading to progressive weakness in the...
MONDO:0008438
Hereditary spastic paraplegia 4 is a neurological condition that primarily affects the lower limbs and is characterized by progressive gait impairment...
MONDO:0013239
MONDO:0012928
Hereditary spastic paraplegia 42 is a pure form of spastic paraplegia that primarily affects the lower limbs, leading to gradually worsening spasticit...
MONDO:0014024
MONDO:0013179
Hereditary spastic paraplegia 44 is a very rare, complex neurological disorder primarily affecting motor function later in life. It is characterized b...
MONDO:0013165
MONDO:0013737
Hereditary spastic paraplegia 46 is a very rare, complex neurological condition that primarily affects motor function and cognitive abilities. It is c...
MONDO:0013551
Hereditary spastic paraplegia 47 is a neurologically based condition characterized by significant motor and cognitive challenges that arise in early c...
Built from MONDO, HPO, ClinicalTrials.gov, FDA, Orphanet, and 7 more public sources. Updated daily.