acropectoral syndrome

Acro-pectoral syndrome is a rare condition that affects the limbs and the upper part of the chest. People with this condition have abnormalities in the hands and feet such as joined fingers (syndactyly) and extra digits (preaxial polydactyly), as well as malformations in the upper portion of the sternum. This syndrome has been observed in 22 individuals from a six-generation Turkish family. It is passed down in families in an autosomal dominant pattern, meaning it can be inherited from just one affected parent.

Common signs of acro-pectoral syndrome include syndactyly, which is the fusion of all fingers and toes, and preaxial polydactyly, meaning extra digits may be present in the hands or feet. Upper sternum malformations are also a key feature seen in people with this condition.

Acro-pectoral syndrome is caused by genetic factors. It is inherited as an autosomal dominant trait. The gene associated with this condition is located on chromosome 7q36, and the known gene related to its manifestation is ACRPS.

Information about treatment options and management is currently limited for this condition.

Information about prognosis, including long-term outcomes and quality of life, is currently limited for this condition.

Information about research and future directions for acro-pectoral syndrome is currently limited. Ongoing studies may provide more insights in the future.