Acute poisoning with a membrane-stabilizing effect is a serious and potentially life-threatening condition. It occurs when drugs that affect the electrical properties of cell membranes are taken in toxic amounts. This can disrupt the normal function of cells, especially in the heart and the nervous system. The drugs most often involved include tricyclic antidepressants, chloroquine, certain beta blockers, class IA antiarrhythmics, carbamazepine, and cocaine. Because of the diverse range of drugs that can lead to this poisoning, the effects and severity can vary widely depending on the specific substance and amount ingested.

Information about symptoms is currently limited for this condition.

Information about causes is currently limited for this condition.