A rare autoimmune encephalitis involving the mesial temporal lobes and clinically characterized by subacute onset (i. e. rapid progression of less than three months) of short-term memory deficits, sei...
Comprehensive, easy-to-understand information about this condition
How we create this content →Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 6, 2026
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 6, 2026
The limited documentation surrounding autoimmune limbic encephalitis is largely due to its rarity, affecting fewer than 10 in 100,000 people. This rarity restricts the scope of systematic clinical studies, making it challenging to gather comprehensive data. Additionally, the absence of identified genetic causes and established inheritance patterns further complicates our understanding of the condition.
The clinical features of autoimmune limbic encephalitis include a range of psychiatric symptoms such as psychosis, depression, and anxiety, occurring in 30-79% of cases. Neurological symptoms are also prominent, with seizures and mental deterioration reported in a similar frequency. Other symptoms may include irritability, lethargy, fever, headache, and increased protein concentration in cerebrospinal fluid, all contributing to the complex clinical picture of this condition.
To navigate your care effectively, consider seeking a neurologist with expertise in autoimmune encephalitis. It may also be beneficial to connect with research centers that specialize in neuroimmunology. For additional support, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Participating in clinical trials may also provide access to new therapies and contribute to research efforts.
Currently, there are two active clinical trials focusing on autoimmune limbic encephalitis. These trials aim to explore potential treatment options and improve understanding of the condition. For more details, you can search for ongoing studies at ClinicalTrials.gov using the following link: https://clinicaltrials.gov/search?cond=autoimmune%20limbic%20encephalitis.
Actionable guidance for navigating care for autoimmune limbic encephalitis
To navigate your care effectively, consider seeking a neurologist with expertise in autoimmune encephalitis. It may also be beneficial to connect with research centers that specialize in neuroimmunology. For additional support, you can explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov. Participating in clinical trials may also provide access to new therapies and contribute to research efforts.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Clinical profile data for this condition is not yet available. Phenotype information may still be loading below.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 6, 2026
Consider asking your healthcare providers these condition-specific questions
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Always consult with qualified healthcare providers for medical guidance.
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AI-curated news mentioning autoimmune limbic encephalitis
Updated Feb 9, 2026
Recent research highlights the association of autoimmune encephalitis with anti-recoverin antibodies, providing insights into potential biomarkers for diagnosis. This discovery may enhance understanding and treatment strategies for affected patients.