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Benign nocturnal alternating hemiplegia of childhood is a rare neurologic disease characterized by recurrent attacks of nocturnal screaming or crying followed or accompanied by unilateral or sometimes bilateral hemiplegia. Disorder is not associated with neurological or developmental impairments but may be associated with mild behavioral abnormalities.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
No clinical trials have been registered for benign familial nocturnal alternating hemiplegia of childhood.
3 publications have been identified in PubMed for benign familial nocturnal alternating hemiplegia of childhood. Research spans Review / Meta-Analysis (100%).
Rissardo JP (2024). [PMID: 39088707](https://pubmed.ncbi.nlm.nih.gov/39088707/). *Rambam Maimonides medical journal*. [Review / Meta-Analysis]
Spoto G (2024). [PMID: 38921008](https://pubmed.ncbi.nlm.nih.gov/38921008/). *Current issues in molecular biology*. [Review / Meta-Analysis]
Auwerx C (2024). [PMID: 39332410](https://pubmed.ncbi.nlm.nih.gov/39332410/). *American journal of human genetics*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 8:35 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center