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cyanide poisoning - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

cyanide poisoning

MONDO:0018754

Overview

Treatments1 FDA approved

Diagnosis

Biomarker and diagnostic research for cyanide poisoning has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for cyanide poisoning, including HYDROXOCOBALAMIN (CYANOKIT, approved 2006). An additional 5 compounds hold orphan drug designation.

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for cyanide poisoning.

45 publications have been identified in PubMed for cyanide poisoning. Research spans Basic Science / Preclinical (27%), Review / Meta-Analysis (20%), and Case Report / Case Series (16%).

Research Type	Count	% of Total
Laboratory research	12	27%

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 6:18 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:466670

Questions for Your Care Team

→What are the benefits and potential side effects of CYANOKIT for managing cyanide poisoning?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Brand Name	Generic Name	Sponsor	Designated	Exclusivity End	Designation Status
Nithiodote	sodium nitrite and sodium thiosulfate	Hope Pharmaceuticals	2008	2018	Designated (drug approved for other indication)
Sodium nitrite/sodium thiosulfate	Sodium nitrite/sodium thiosulfate	Keystone Pharmaceuticals, Inc.	2007	—	Designated
Amyl nitrite, sodium nitrite, sodium thiosulfate	Amyl nitrite, sodium nitrite, sodium thiosulfate	Akorn, Inc.	2006	—	Designated
Sodium thiosulfate and sodium nitrite	Sodium thiosulfate and sodium nitrite	Akorn, Inc.	2006	—	Designated
Sodium thiosulfate, sodium nitrite, amyl nitrite	Sodium thiosulfate, sodium nitrite, amyl nitrite	Keystone Pharmaceuticals, Inc.	2006	—	Designated

Kisho

cyanide poisoning

Overview

Diagnosis

Treatment

Approved Therapies

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

Questions for Your Care Team

Questions for Your Care Team

Orphan Drug Designations

Clinical Trials

Recent Publications

cyanide poisoning

Overview

Diagnosis

Treatment

Approved Therapies

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Orphan Drug Designations

Clinical Trials

Recent Publications