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A WHO grade I large cystic tumor that occurs almost exclusively in infants, with a prominent desmoplastic stroma having a neuroepithelial population consisting mainly of neoplastic astrocytes. It involves the superficial cerebral cortex and leptomeninges, and often attaches to the dura. Although clinically it presents as large tumor, it generally has a good prognosis following surgical resection. (Adapted from WHO)
1 clinical trial registered. Interventions under study include drug therapy. Pipeline includes 1 PHASE4. Research is primarily industry-sponsored.
5 publications have been identified in PubMed for desmoplastic infantile astrocytoma. Research spans Review / Meta-Analysis (40%), Case Report / Case Series (40%), and Basic Science / Preclinical (20%).
Kulac I (2026). [PMID: 41568174](https://pubmed.ncbi.nlm.nih.gov/41568174/). *Neurooncol Adv*. [Basic Science / Preclinical]
Mezzacappa FM (2026). [PMID: 35015431](https://pubmed.ncbi.nlm.nih.gov/35015431/). *Unknown Journal*. [Review / Meta-Analysis]
Wang Q (2025). [PMID: 41450915](https://pubmed.ncbi.nlm.nih.gov/41450915/). *Front Oncol*. [Case Report / Case Series]
Lampros M (2025). [PMID: 41123688](https://pubmed.ncbi.nlm.nih.gov/41123688/). *Childs Nerv Syst*. [Review / Meta-Analysis]
Jahani S (2024). [PMID: 39114838](https://pubmed.ncbi.nlm.nih.gov/39114838/). *Clin Case Rep*. [Case Report / Case Series]
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:08 PM UTC
Genetic and Rare Diseases Info Center
AI-curated news mentioning desmoplastic infantile astrocytoma
Updated Sep 9, 2026
A case study highlights suprasellar desmoplastic infantile ganglioglioma in a 7-month-old infant, emphasizing its rarity as a diagnostic consideration for suprasellar masses in infants. This research contributes to the understanding of this uncommon tumor type.