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dysgerminoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

dysgerminoma

MONDO:0003002

Also known as:dysgerminoma (disease)dysgerminoma, malignant

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Overview

A malignant germ cell tumor characterized by the presence of a monotonous primitive germ cell population. The neoplastic cells form aggregates and have an abundant pale cytoplasm and uniform nuclei. The aggregates of the germ cells are separated by fibrous septa which contain inflammatory cells, mostly T-lymphocytes. It arises primarily in the ovaries, but can occur both primarily and secondarily at other sites, particularly the central nervous system. It responds to chemotherapy and radiotherapy. Its prognosis is related to the tumor stage.

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for dysgerminoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include drug therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.

83 publications have been identified in PubMed for dysgerminoma. Research spans Case Report / Case Series (55%), Epidemiology / Natural History (16%), and Basic Science / Preclinical (12%).

Research Type	Count	% of Total
Patient case studies	46	55%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 1:11 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
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dysgerminoma

Overview

Diagnosis

Research Landscape

Medical References

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Questions for Your Care Team

Questions for Your Care Team

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