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eastern equine encephalitis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

eastern equine encephalitis

MONDO:0005736

Also known as:Eastern equine encephalomyelitisNeuroinvasive Eastern equine encephalitis virus infectionEEE

Overview

Eastern equine encephalitis (EEE) is an acute arboviral infection caused by an alphavirus of the Togaviridae family transmitted by an infected mosquito, that is characterized by the onset of flulike symptoms including fever, chills, weakness, headache, vomiting, abdominal pain with diarrhea, myalgia, leucocytosis, and hematuria, rapidly progressing to diffuse central nervous system (CNS) involvement with confusion, somnolence, or even coma. Seizures, which may progress to status epilepticus and neurologic sequelae, cranial nerve palsies, and photophobia may occur. EEE is associated with a high rate of morbidity and mortality.

Diagnosis

Biomarker and diagnostic research for eastern equine encephalitis has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for eastern equine encephalitis.

80 publications have been identified in PubMed for eastern equine encephalitis. Research spans Basic Science / Preclinical (36%), Epidemiology / Natural History (34%), and Review / Meta-Analysis (9%).

Research Type	Count	% of Total
Laboratory research	29	36%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:30 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:83594

GARD

Genetic and Rare Diseases Info Center

GARD:10821

Questions for Your Care Team

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eastern equine encephalitis

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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