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ganglioneuroma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

ganglioneuroma

MONDO:0005033

Also known as:ganglioneuroma (Schwannian Stroma-dominant)ganglioneuroma (disease)ganglioneuroma, benign

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Overview

A benign neuroblastic tumor of the sympathetic nervous system that occurs in childhood. Ganglioneuroma typically arises from the sympathetic trunk in the mediastinum. Histologic features include spindle cell proliferation (resembling a neurofibroma) and the presence of large ganglion cells. Common presenting features include a palpable abdominal mass, hepatomegaly, and a thoracic mass detected on routine chest X-ray.

Clinical Trials5 registered · 3 recruiting

Diagnosis

Biomarker and diagnostic research for ganglioneuroma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

5 clinical trials registered, 3 recruiting. Interventions under study include other interventions, procedural interventions, and drug therapy. Pipeline includes 1 EARLY_PHASE1, 1 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT04040088](https://clinicaltrials.gov/study/NCT04040088)

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 11:13 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:251992

GARD

Genetic and Rare Diseases Info Center

GARD:20731

Questions for Your Care Team

→Are any of the 5 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	121	69%
Research summaries	15	9%
Clinical study results	13	7%
Testing and diagnosis research	10	6%
Laboratory research	9	5%
Disease patterns and progression	6	3%
Other research	1	1%
New treatment approaches	1	1%

Kisho

ganglioneuroma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Mandibular malignant peripheral nerve sheath tumour in a patient with a history of radiotherapy for cerebellopontine angle ganglioneuroma.

ganglioneuroma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Mandibular malignant peripheral nerve sheath tumour in a patient with a history of radiotherapy for cerebellopontine angle ganglioneuroma.