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Conditions in which the primary symptom is headache and the headache cannot be attributed to any known causes.
Biomarker and diagnostic research for hypnic headache has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for hypnic headache.
106 publications have been identified in PubMed for hypnic headache. Kisho has analyzed 79 by research type. Research spans Review / Meta-Analysis (44%), Epidemiology / Natural History (20%), and Clinical Trial Publication (15%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 35 | 44% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 10:41 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Disease patterns and progression
16 |
20% |
Clinical study results | 12 | 15% |
Laboratory research | 11 | 14% |
Patient case studies | 3 | 4% |
Testing and diagnosis research | 1 | 1% |
New treatment approaches | 1 | 1% |
Larsen CG (2026). [PMID: 41614252](https://pubmed.ncbi.nlm.nih.gov/41614252/). *Ugeskr Laeger*. [Review / Meta-Analysis]
Villar-Martinez MD (2026). [PMID: 41324222](https://pubmed.ncbi.nlm.nih.gov/41324222/). *Curr Opin Neurol*. [Review / Meta-Analysis]
Correnti E (2026). [PMID: 41751188](https://pubmed.ncbi.nlm.nih.gov/41751188/). *Biomedicines*. [Review / Meta-Analysis]
van Liefland M (2026). [PMID: 41713202](https://pubmed.ncbi.nlm.nih.gov/41713202/). *Sleep Med*. [Review / Meta-Analysis]
Danelakis A (2026). [PMID: 40326299](https://pubmed.ncbi.nlm.nih.gov/40326299/). *Brain*. [Basic Science / Preclinical]
Wiley AT (2025). [PMID: 40238974](https://pubmed.ncbi.nlm.nih.gov/40238974/). *Am Fam Physician*. [Review / Meta-Analysis]
Chang TP (2025). [PMID: 39932582](https://pubmed.ncbi.nlm.nih.gov/39932582/). *J Neurol*. [Epidemiology / Natural History]
Kirazli G (2025). [PMID: 39268858](https://pubmed.ncbi.nlm.nih.gov/39268858/). *Laryngoscope*. [Epidemiology / Natural History]
Tana C (2025). [PMID: 40338487](https://pubmed.ncbi.nlm.nih.gov/40338487/). *Adv Ther*. [Review / Meta-Analysis]
Yuan H (2025). [PMID: 40011818](https://pubmed.ncbi.nlm.nih.gov/40011818/). *J Headache Pain*. [Basic Science / Preclinical]