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Features include very common findings: Abnormal blistering of the skin, Neutrophilic infiltration of the skin, and Skin vesicle; and common findings: Pruritus, Generalized abnormality of skin, Pain, and Autoimmune antibody positivity and others. 19 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Skin | 8 | Abnormal blistering of the skin, Neutrophilic infiltration of the skin, Skin vesicle |
Lab test results |
Phenotype severity distribution: 3 very common features, 10 common features.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for IgA pemphigus.
15 publications have been identified in PubMed for IgA pemphigus. Research spans Case Report / Case Series (53%), Review / Meta-Analysis (33%), and Epidemiology / Natural History (13%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 8 | 53% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 12:59 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about IgA pemphigus
Autoimmune antibody positivity, Increased circulating IgA concentration, Monoclonal elevation of circulating IgA |
Blood and immune system | 2 | Neutrophilic infiltration of the skin, Autoimmune antibody positivity |
Brain and nerves | 1 | Pain |
Digestive system | 1 | Ulcerative colitis |
5 |
33% |
Disease patterns and progression | 2 | 13% |
Quintarelli L (2026). [PMID: 41072932](https://pubmed.ncbi.nlm.nih.gov/41072932/). *Clinical and experimental dermatology*. [Case Report / Case Series]
Adam Z (2026). [PMID: 42172113](https://pubmed.ncbi.nlm.nih.gov/42172113/). *Klin Onkol*. [Review / Meta-Analysis]
Markwitz M (2026). [PMID: 42123145](https://pubmed.ncbi.nlm.nih.gov/42123145/). *J Clin Med*. [Case Report / Case Series]
Hong S (2026). [PMID: 42176709](https://pubmed.ncbi.nlm.nih.gov/42176709/). *J Am Acad Dermatol*. [Review / Meta-Analysis]
Li J (2025). [PMID: 40491920](https://pubmed.ncbi.nlm.nih.gov/40491920/). *Frontiers in immunology*. [Epidemiology / Natural History]
Craus D (2025). [PMID: 40728582](https://pubmed.ncbi.nlm.nih.gov/40728582/). *Dermatologie (Heidelberg, Germany)*. [Review / Meta-Analysis]
Geng RSQ (2025). [PMID: 39881552](https://pubmed.ncbi.nlm.nih.gov/39881552/). *Journal of cutaneous medicine and surgery*. [Review / Meta-Analysis]
Garg S (2025). [PMID: 40557735](https://pubmed.ncbi.nlm.nih.gov/40557735/). *Pediatric dermatology*. [Case Report / Case Series]
DI Michele E (2025). [PMID: 40248966](https://pubmed.ncbi.nlm.nih.gov/40248966/). *Italian journal of dermatology and venereology*. [Case Report / Case Series]
Olvera-Rodriguez V (2025). [PMID: 39825175](https://pubmed.ncbi.nlm.nih.gov/39825175/). *International journal of dermatology*. [Case Report / Case Series]