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Meralgia paresthetica is a condition characterized by tingling, numbness and burning pain in the outer thigh. These symptoms may become worse after walking or standing. The condition generally only affects one side of the body, although both sides may be involved in up to 20% of cases. Meralgia paresthetica is caused by compression of the lateral femoral cutaneous nerve (a sensory nerve to the skin on the outer thigh). This may be associated with a variety of causes such as tight clothing, obesity, and/or pregnancy. Treatment is based on the signs and symptoms present in each person and may include medications to manage pain. In most cases, conservative treatment by wearing looser clothing and/or losing weight generally resolves symptoms.
Biomarker and diagnostic research for meralgia paresthetica has been reported in the published literature.
2 clinical trials registered, 2 recruiting. Interventions under study include other interventions and medical devices. Pipeline includes 2 NA. Research is primarily sponsored by academic and government institutions.
134 publications have been identified in PubMed for meralgia paresthetica. Research spans Case Report / Case Series (29%), Review / Meta-Analysis (26%), and Epidemiology / Natural History (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 38 |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 12:58 PM UTC
Genetic and Rare Diseases Info Center
Research summaries | 34 | 26% |
Disease patterns and progression | 18 | 14% |
Clinical study results | 15 | 12% |
Laboratory research | 14 | 11% |
Other research | 5 | 4% |
Testing and diagnosis research | 3 | 2% |
New treatment approaches | 3 | 2% |
Cecia A (2026). [PMID: 41175856](https://pubmed.ncbi.nlm.nih.gov/41175856/). *J Clin Neurosci*. [Review / Meta-Analysis]
Chow WD (2026). [PMID: 42081837](https://pubmed.ncbi.nlm.nih.gov/42081837/). *J Neurosurg Case Lessons*. [Case Report / Case Series]
Black AC (2026). [PMID: 35881745](https://pubmed.ncbi.nlm.nih.gov/35881745/). *Unknown Journal*. [Other]
Vatavu O (2026). [PMID: 41549412](https://pubmed.ncbi.nlm.nih.gov/41549412/). *J Peripher Nerv Syst*. [Case Report / Case Series]
Vallejos G J (2026). [PMID: 41869114](https://pubmed.ncbi.nlm.nih.gov/41869114/). *Cureus*. [Review / Meta-Analysis]
Baruchi S (2026). [PMID: 41551868](https://pubmed.ncbi.nlm.nih.gov/41551868/). *Brain Spine*. [Epidemiology / Natural History]
Hardy J (2026). [PMID: 41500366](https://pubmed.ncbi.nlm.nih.gov/41500366/). *Ann Anat*. [Basic Science / Preclinical]
Maalouf G (2026). [PMID: 41728983](https://pubmed.ncbi.nlm.nih.gov/41728983/). *Arthritis Rheumatol*. [Epidemiology / Natural History]
Baron-Franco B (2026). [PMID: 42074896](https://pubmed.ncbi.nlm.nih.gov/42074896/). *J Clin Med*. [Case Report / Case Series]
Anastasiou G (2026). [PMID: 41651186](https://pubmed.ncbi.nlm.nih.gov/41651186/). *Diabetes Res Clin Pract*. [Epidemiology / Natural History]