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polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG

MONDO:0018977

Also known as:anti-MAG neuropathyneuropathy associated with monoclonal IgM antibodies to myelin-associated glycoprotein

Find Clinical TrialsTrials

Overview

Polyneuropathy associated with IgM monoclonal gammapathy (MG) with anti-MAG (myelin-associated-glycoprotein) activity is a demyelinating polyneuropathy characterized clinically by sensory ataxia, tremor, paresthesia, and impaired gait.

Clinical Trials2 registered · 2 recruiting

Diagnosis

Biomarker and diagnostic research for polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

2 clinical trials registered, 2 recruiting. Interventions under study include drug therapy and other interventions. Pipeline includes 1 PHASE3. Research is primarily sponsored by academic and government institutions.

35 publications have been identified in PubMed for polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG. Research spans Review / Meta-Analysis (37%), Case Report / Case Series (34%), and Basic Science / Preclinical (11%).

Research Type	Count	% of Total
Research summaries	13

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 3:34 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:639

GARD

Genetic and Rare Diseases Info Center

GARD:13173

Questions for Your Care Team

→Are any of the 2 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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polyneuropathy associated with IgM monoclonal gammapathy with anti-MAG

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications